Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18036344 | 0.91 | MAPT (0.40) | P2RX3P2RX2MAPT | |
| SCHEMBL10243997 | 0.85 | P2RX3 (0.55) | P2RX3P2RX2 | |
| SCHEMBL10243493 | 0.85 | P2RX3 (0.55) | P2RX3P2RX2 | |
| SCHEMBL18036401 | 0.85 | P2RX3 (0.41) | P2RX3P2RX2MAPT | |
| SCHEMBL18036427 | 0.84 | P2RX3 (0.40) | P2RX3P2RX2MAPTFAAHMGLL | |
| SCHEMBL18036400 | 0.84 | P2RX3 (0.53) | P2RX3P2RX2MAPT | |
| SCHEMBL18036343 | 0.84 | P2RX3 (0.40) | P2RX3P2RX2MAPTFAAHMGLL | |
| SCHEMBL18036457 | 0.84 | P2RX3 (0.53) | P2RX3P2RX2MAPT | |
| SCHEMBL18036369 | 0.84 | TP53 (0.37) | P2RX3P2RX2MAPTFAAH | |
| SCHEMBL18036397 | 0.84 | P2RX3 (0.45) | P2RX3P2RX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2592070-B1 | Tetrazole-substituted arylamides | HOFFMANN LA ROCHE (CH) | 2016-08-31 | — | — | EP | claimed |