Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10243044 | 0.85 | TSHR (0.47) | KMT2ATSHRPTK2CNR1CNR2 | |
| SCHEMBL18036403 | 0.82 | KMT2A (0.46) | KMT2ATSHRMAPTNOTUMTP53 | |
| SCHEMBL18036428 | 0.80 | KMT2A (0.44) | KMT2ATSHRMAPTCNR1NOTUM | |
| SCHEMBL18036430 | 0.80 | KMT2A (0.44) | KMT2ATSHRMAPTNOTUMTP53 | |
| SCHEMBL18036333 | 0.80 | P2RX3 (0.47) | KMT2APTK2MAPTCNR1CNR2 | |
| SCHEMBL18036361 | 0.80 | KMT2A (0.44) | KMT2ATSHRMAPTNOTUMTP53 | |
| SCHEMBL18036460 | 0.79 | KMT2A (0.45) | KMT2A | |
| SCHEMBL18036357 | 0.79 | KMT2A (0.41) | KMT2ATSHRPTK2MAPTTP53 | |
| SCHEMBL18036362 | 0.78 | KMT2A (0.44) | KMT2ATSHRMAPTLMNAPOLB | |
| SCHEMBL18036383 | 0.77 | KMT2A (0.43) | KMT2ATSHRMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2592070-B1 | Tetrazole-substituted arylamides | HOFFMANN LA ROCHE (CH) | 2016-08-31 | — | — | EP | claimed |