Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.45 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18036306 | 0.91 | P2RX3 (0.44) | P2RX3P2RX2 | |
| SCHEMBL18036358 | 0.91 | P2RX3 (0.44) | P2RX3P2RX2 | |
| SCHEMBL18036351 | 0.91 | P2RX3 (0.44) | P2RX3P2RX2GAATRPV1LMNA | |
| SCHEMBL18036400 | 0.91 | P2RX3 (0.53) | P2RX3P2RX2GAATRPV1LMNA | |
| SCHEMBL18036457 | 0.91 | P2RX3 (0.53) | P2RX3P2RX2GAATRPV1LMNA | |
| SCHEMBL18036445 | 0.90 | P2RX3 (0.47) | P2RX3P2RX2GAATRPV1LMNA | |
| SCHEMBL18036381 | 0.88 | P2RX3 (0.45) | P2RX3P2RX2GAATRPV1LMNA | |
| SCHEMBL18036397 | 0.88 | P2RX3 (0.45) | P2RX3P2RX2GAATRPV1LMNA | |
| SCHEMBL10244019 | 0.87 | P2RX3 (0.57) | P2RX3P2RX2 | |
| SCHEMBL10244035 | 0.87 | P2RX3 (0.57) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2592070-B1 | Tetrazole-substituted arylamides | HOFFMANN LA ROCHE (CH) | 2016-08-31 | — | — | EP | claimed |