Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28041713 | 0.83 | RXFP1 (0.41) | RXFP1PTGS1PTGS2HCAR3HCAR2 | |
| SCHEMBL15148770 | 0.81 | CYP1A2 (0.43) | RXFP1HTT | |
| SCHEMBL15148352 | 0.81 | CYP1A2 (0.43) | RXFP1HTT | |
| SCHEMBL19789285 | 0.81 | CYP1A2 (0.43) | RXFP1HTT | |
| SCHEMBL375420 | 0.70 | RXFP1 (0.45) | RXFP1PTGS1PTGS2HCAR2 | |
| SCHEMBL18040235 | 0.68 | ADA (0.47) | HCAR3HCAR2 | |
| SCHEMBL29663112 | 0.68 | ADA (0.47) | HCAR3HCAR2 | |
| SCHEMBL29663447 | 0.68 | ADA (0.47) | HCAR3HCAR2 | |
| SCHEMBL19780550 | 0.68 | HTR2A (0.32) | RXFP1PTGS1PTGS2HCAR3HCAR2 | |
| SCHEMBL25274273 | 0.67 | RXFP1 (0.42) | RXFP1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3064502-A1 | IMIDAZOPYRROLIDINONE COMPOUNDS | Novartis AG (CH) | 2016-09-07 | — | — | EP | disclosed |