SCHEMBL18040263

SCHEMBL18040263

CC(C)(C)CC(Cc1ccc(O)c(C(C)(C)C)c1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.43
ALOX15 P16050 2/20 0.42
HSD17B10 Q99714 2/20 0.42
ALDH1A1 P00352 2/20 0.42
NR1I2 O75469 1/20 0.42
LMNA P02545 1/20 0.42
CYP2C9 P11712 1/20 0.42
MIF P14174 1/20 0.42
TYR P14679 1/20 0.42
HTT P42858 1/20 0.42
NFE2L2 Q16236 1/20 0.42
KDM4E B2RXH2 1/20 0.42
USP2 O75604 1/20 0.42
EGFR P00533 1/20 0.42
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
PTGS1 P23219 1/20 0.42
HTR2A P28223 1/20 0.42
PTGS2 P35354 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30891619 0.91 KDM6B (0.45) KDM6BALOX15HSD17B10ALDH1A1NR1I2
SCHEMBL28170347 0.88 GAA (0.49) KDM6BALOX15HSD17B10ALDH1A1NR1I2
SCHEMBL6750769 0.87 GAA (0.45) KDM6BALOX15HSD17B10ALDH1A1NR1I2
SCHEMBL2131061 0.86 KDM6B (0.41) KDM6BALOX15HSD17B10ALDH1A1NR1I2
SCHEMBL4145724 0.85 ATM (0.43) ALOX15HSD17B10ALDH1A1NR1I2LMNA
SCHEMBL23699000 0.84 ESR1 (0.47) KDM6BALOX15HSD17B10ALDH1A1NR1I2
SCHEMBL30077243 0.83 GAA (0.40) KDM6BALOX15HSD17B10ALDH1A1NR1I2
SCHEMBL2133184 0.83 GAA (0.40) KDM6BALOX15HSD17B10ALDH1A1NR1I2
SCHEMBL604340 0.82 GAA (0.50) HSP90AA1HSP90AB1GAAXBP1ATM
SCHEMBL9845237 0.82 KDM6B (0.45) KDM6BALOX15HSD17B10ALDH1A1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3336155-B1 HOT MELT ADHESIVE COMPRISING ISOTHIAZOLINONE FUNGICIDES HENKEL AG & CO KGAA (DE) 2024-07-31 EP disclosed
US-11332646-B2 Hot melt adhesive comprising isothiazolinone fungicides HENKEL AG & CO. KGAA (DE) 2022-05-17 US disclosed
EP-3064560-B1 Thermally conductive adhesive HENKEL AG & CO KGAA (DE) 2022-05-04 EP disclosed
US-10689551-B2 Thermally conductive adhesive HENKEL AG & CO. KGAA (DE) 2020-06-23 US disclosed
US-20190309194-A1 HOT MELT ADHESIVE COMPRISING ISOTHIAZOLINONE FUNGICIDES HENKEL AG & CO., KGAA (DE) 2019-10-10 US disclosed
US-20190085219-A1 ELECTRICALLY CONDUCTIVE, HOT-MELT ADHESIVE OR MOULDING COMPOSITION HENKEL AG & CO KGAA (DE) 2019-03-21 US disclosed
WO-2018114305-A1 HOT MELT ADHESIVE COMPRISING ISOTHIAZOLINONE FUNGICIDES HENKEL AG & CO. KGAA (DE) 2018-06-28 WO disclosed
EP-3336155-A1 HOT MELT ADHESIVE COMPRISING ISOTHIAZOLINONE FUNGICIDES Henkel AG & Co. KGaA (DE) 2018-06-20 EP disclosed
EP-3303494-A1 HIGH THERMALLY CONDUCTIVE LOW PRESSURE MOULDABLE HOTMELT Henkel AG & Co. KGaA (DE) 2018-04-11 EP disclosed
US-20180094171-A1 HIGH THERMALLY CONDUCTIVE LOW PRESSURE MOULDABLE HOTMELT HENKEL ELECTRONIC MATERIALS (BELGIUM) N.V. (BE) 2018-04-05 US disclosed
US-20170362473-A1 THERMALLY CONDUCTIVE ADHESIVE HENKEL AG & CO. KGAA (DE) 2017-12-21 US disclosed
WO-2017182621-A1 AN ELECTRICALLY CONDUCTIVE, HOT-MELT ADHESIVE OR MOULDING COMPOSITION HENKEL AG & CO. KGAA (DE) 2017-10-26 WO disclosed
EP-3236479-A1 AN ELECTRICALLY CONDUCTIVE, HOT-MELT ADHESIVE OR MOULDING COMPOSITION Henkel AG & Co. KGaA (DE) 2017-10-25 EP disclosed
WO-2016198425-A1 HIGH THERMALLY CONDUCTIVE LOW PRESSURE MOULDABLE HOTMELT HENKEL AG & CO. KGAA (DE) 2016-12-15 WO disclosed
EP-3064560-A1 Thermally conductive adhesive Henkel AG & Co. KGaA (DE) 2016-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190309194-A1 HOT MELT ADHESIVE COMPRISING ISOTHIAZOLINONE FUNGICIDES RICTOR, HSF1, ICAM1 KDM6B 2242/4885ALOX15 366/4885HSD17B10 386/4885
US-11332646-B2 Hot melt adhesive comprising isothiazolinone fungicides RICTOR, HSF1, ICAM1 KDM6B 2242/4885ALOX15 366/4885HSD17B10 386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.