Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.75 |
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16808325 | 0.98 | SLC34A2 (0.79) | SLC34A2GPR52ROCK2ROCK1MAPK14 | |
| SCHEMBL46770 | 0.95 | SLC34A2 (0.82) | SLC34A2GPR52ROCK2ROCK1MAPK14 | |
| SCHEMBL44914 | 0.95 | SLC34A2 (0.82) | SLC34A2GPR52ROCK2ROCK1MAPK14 | |
| SCHEMBL47055 | 0.95 | SLC34A2 (0.82) | SLC34A2GPR52ROCK2ROCK1MAPK14 | |
| SCHEMBL6001829 | 0.95 | SLC34A2 (0.82) | SLC34A2GPR52ROCK2ROCK1MAPK14 | |
| SCHEMBL15444480 | 0.93 | SLC34A2 (0.70) | SLC34A2GPR52ROCK2ROCK1MAPK14 | |
| SCHEMBL10290125 | 0.92 | SLC34A2 (0.70) | SLC34A2GPR52ROCK2ROCK1MLYCD | |
| SCHEMBL15432903 | 0.92 | SLC34A2 (0.70) | SLC34A2GPR52ROCK2ROCK1MAPK14 | |
| SCHEMBL16355247 | 0.91 | SLC34A2 (0.68) | SLC34A2GPR52ROCK2ROCK1KDM1A | |
| SCHEMBL15432885 | 0.90 | SLC34A2 (0.69) | SLC34A2GPR52ROCK2ROCK1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2591354-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2016-09-07 | — | — | EP | disclosed |