Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.47 |
| ▸ | PAICS | P22234 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSC | P53634 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16722323 | 0.90 | BRD4 (0.52) | BRD4PAICSTTKCTSKCTSC | |
| SCHEMBL16721546 | 0.89 | BRD4 (0.60) | BRD4PAICSTTKPIK3CD | |
| SCHEMBL16721233 | 0.87 | BRD4 (0.58) | BRD4PAICSTTKCTSKCTSC | |
| SCHEMBL21638627 | 0.87 | BRD4 (0.46) | BRD4PAICSNAMPT | |
| SCHEMBL21638594 | 0.86 | BRD4 (0.64) | BRD4 | |
| SCHEMBL21638456 | 0.86 | BRD4 (0.49) | BRD4NAMPT | |
| SCHEMBL21638680 | 0.85 | BRD4 (0.48) | BRD4NAMPT | |
| SCHEMBL21638678 | 0.85 | BRD4 (0.48) | BRD4CTSKCTSCNAMPTHCRTR1 | |
| SCHEMBL21638444 | 0.84 | BRD4 (0.47) | BRD4TTKHCRTR1HCRTR2 | |
| SCHEMBL21638695 | 0.84 | BRD4 (0.47) | BRD4NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160256458-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS, INC. | 2016-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160256458-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | BRD4, BRPF3, BRD7 | BRD4 1/4885PAICS 4514/4885TTK 4015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.