Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 0.48 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | GPER1 | Q99527 | 3/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21638456 | 0.92 | BRD4 (0.49) | BRD4NAMPTGPER1PRMT5WDR77 | |
| SCHEMBL21638620 | 0.91 | BRD4 (0.46) | BRD4NAMPTGPER1 | |
| SCHEMBL21638712 | 0.90 | BRD4 (0.47) | BRD4NAMPTIDH1 | |
| SCHEMBL21638678 | 0.89 | BRD4 (0.48) | BRD4NAMPTGPER1IDH1 | |
| SCHEMBL21638490 | 0.89 | BRD4 (0.46) | BRD4NAMPT | |
| SCHEMBL21638725 | 0.88 | BRD4 (0.45) | BRD4NAMPTGPER1PRMT5WDR77 | |
| SCHEMBL16722365 | 0.88 | BRD4 (0.56) | BRD4NAMPTGPER1 | |
| SCHEMBL21638689 | 0.88 | BRD4 (0.47) | BRD4NAMPTGPER1 | |
| SCHEMBL21638695 | 0.87 | BRD4 (0.47) | BRD4NAMPT | |
| SCHEMBL21638444 | 0.87 | BRD4 (0.47) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071205-B1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-02-05 | — | — | EP | disclosed |