SCHEMBL1804359

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1802256	0.90	KMT2A (0.47)	CYP1A2CYP2C19CYP2D6TSHRSLC6A4
	SCHEMBL1804690	0.87	KMT2A (0.46)	TSHRKMT2ARAB9AMAPTMEN1
	SCHEMBL12551321	0.86	KMT2A (0.39)	CYP1A2CYP2C19CYP2D6TSHRSLC6A4
	SCHEMBL1805166	0.86	NSD2 (0.43)	CYP1A2CYP2C19CYP2D6TSHRKMT2A
	SCHEMBL1804980	0.85	KDM4E (0.45)	CYP1A2CYP2C19CYP2D6TSHRKMT2A
	SCHEMBL1807706	0.83	GRM1 (0.40)	CYP1A2CYP2C19KMT2ARAB9AALDH1A1
	SCHEMBL1802753	0.81	NR3C2 (0.40)	CYP1A2CYP2C19CYP2D6TSHRSLC6A4
	SCHEMBL29028657	0.80	CYP2C19 (0.46)	CYP1A2CYP2C19CYP2D6TSHRSLC6A4
	SCHEMBL25208675	0.79	KMT2A (0.51)	CYP1A2CYP2C19CYP2D6TSHRSLC6A4
	SCHEMBL21899368	0.79	CTNNB1 (0.40)	KMT2ARAB9AMAPTMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.