SCHEMBL18044009

SCHEMBL18044009

Cc1cccc(C(=O)O)c1CCC1(C)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18044011 0.87 FPR2 (0.77) FPR2
SCHEMBL14935725 0.86 FPR2 (0.80) FPR2
SCHEMBL14935440 0.84 FPR2 (1.00) FPR2
SCHEMBL18044003 0.84 FPR2 (0.74) FPR2
SCHEMBL14935467 0.80 FPR2 (0.84) FPR2
SCHEMBL14935274 0.80 FPR2 (0.77) FPR2
SCHEMBL14935703 0.80 FPR2 (1.00) FPR2
SCHEMBL30198236 0.80 FPR2 (1.00) FPR2
SCHEMBL14945864 0.79 FPR2 (1.00) FPR2
SCHEMBL14935573 0.79 FPR2 (1.00) FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3103797-B1 2,5-DIOXOIMIDAZOLIDIN-1-YL-3-PHENYLUREA DERIVATIVES AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS ALLERGAN INC (US) 2019-04-10 EP disclosed
EP-3103797-A1 2,5-DIOXOIMIDAZOLIDIN-1-YL-3-PHENYLUREA DERIVATIVES AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS ALLERGAN, INC. (US) 2016-12-14 EP disclosed
EP-2776403-B1 2,5-DIOXOIMIDAZOLIDIN-1-YL-3-PHENYLUREA DERIVATIVES AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS ALLERGAN INC (US) 2016-09-14 EP disclosed