SCHEMBL18044014

SCHEMBL18044014

CC(C)C1(CC(=O)NCC(C(=O)O)C(C)(C)C)NC(=O)N(NC(=O)Nc2ccc(Br)cc2)C1=O

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20873587 0.85 FPR2 (0.73) FPR2
SCHEMBL14935330 0.85 FPR2 (0.82) FPR2
SCHEMBL14935409 0.83 FPR2 (0.70) FPR2
SCHEMBL14935476 0.83 FPR2 (1.00) FPR2
SCHEMBL14935578 0.83 FPR2 (1.00) FPR2
SCHEMBL14945911 0.83 FPR2 (0.72) FPR2
SCHEMBL14935717 0.83 FPR2 (0.79) FPR2
SCHEMBL23114217 0.82 FPR2 (0.84) FPR2
SCHEMBL16973609 0.82 FPR2 (0.84) FPR2
SCHEMBL14935539 0.82 FPR2 (0.77) FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3103797-B1 2,5-DIOXOIMIDAZOLIDIN-1-YL-3-PHENYLUREA DERIVATIVES AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS ALLERGAN INC (US) 2019-04-10 EP claimed
EP-2776403-B1 2,5-DIOXOIMIDAZOLIDIN-1-YL-3-PHENYLUREA DERIVATIVES AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS ALLERGAN INC (US) 2016-09-14 EP claimed
EP-3103797-A1 2,5-DIOXOIMIDAZOLIDIN-1-YL-3-PHENYLUREA DERIVATIVES AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS ALLERGAN, INC. (US) 2016-12-14 EP disclosed