Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SENP2 | Q9HC62 | 4/20 | 0.54 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.54 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.54 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.54 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.52 |
| ▸ | SLC7A11 | Q9UPY5 | 4/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14997196 | 1.00 | APP (0.55) | APPALDH1A1THRBHPGDALOX12 | |
| SCHEMBL14988577 | 0.99 | APP (0.54) | APPALDH1A1THRBHPGDALOX12 | |
| SCHEMBL14988580 | 0.99 | APP (0.54) | APPALDH1A1THRBHPGDALOX12 | |
| SCHEMBL23787709 | 0.89 | APP (0.67) | APPALDH1A1THRBHPGDALOX12 | |
| SCHEMBL14988579 | 0.89 | SLC7A11 (0.56) | APPALDH1A1THRBHPGDALOX12 | |
| SCHEMBL18044299 | 0.84 | APP (0.78) | APPALDH1A1THRBHPGDALOX12 | |
| SCHEMBL15120267 | 0.84 | APP (0.78) | APPALDH1A1THRBHPGDALOX12 | |
| SCHEMBL14988421 | 0.83 | APP (0.77) | APPALDH1A1THRBHPGDALOX12 | |
| SCHEMBL14988419 | 0.83 | APP (0.77) | APPALDH1A1THRBHPGDALOX12 | |
| SCHEMBL18044288 | 0.82 | SENP2 (0.66) | APPALDH1A1THRBHPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2599771-B1 | NAPHTHALENE DERIVATIVE | DAITO CHEMIX CORP (JP) | 2016-09-14 | — | — | EP | claimed |