SCHEMBL18044784

SCHEMBL18044784

Oc1ccc(Cc2cc(O)c(O)c(O)c2)cc1O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.81
CA2 P00918 1/20 0.81
CA4 P22748 1/20 0.81
CA6 P23280 1/20 0.81
IDH1 O75874 1/20 0.65
MAPT P10636 7/20 0.59
KDM4E B2RXH2 5/20 0.56
ALOX15 P16050 3/20 0.56
MAPK1 P28482 3/20 0.56
SNCA P37840 3/20 0.56
ALDH1A1 P00352 3/20 0.56
ADRA2A P08913 2/20 0.56
DRD2 P14416 2/20 0.56
DRD1 P21728 2/20 0.56
DRD4 P21917 2/20 0.56
DRD5 P21918 2/20 0.56
SLC6A2 P23975 2/20 0.56
DRD3 P35462 2/20 0.56
RECQL P46063 2/20 0.56
SLC6A3 Q01959 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15722470 0.90 CA1 (0.90) CA1CA2CA4CA6IDH1
SCHEMBL108093 0.90 CA1 (1.00) CA1CA2CA4CA6IDH1
SCHEMBL109054 0.87 CA1 (0.94) CA1CA2CA4CA6IDH1
SCHEMBL12022712 0.87 CA1 (0.68) CA1CA2CA4CA6IDH1
SCHEMBL11408792 0.84 CA1 (0.52) CA1CA2CA4CA6IDH1
SCHEMBL15387372 0.83 CA1 (0.85) CA1CA2CA4CA6IDH1
SCHEMBL278268 0.81 CA1 (0.81) CA1CA2CA4CA6IDH1
SCHEMBL107211 0.81 CA1 (0.81) CA1CA2CA4CA6IDH1
SCHEMBL278270 0.81 ESR1 (0.67) CA1CA2CA4CA6IDH1
SCHEMBL1584791 0.79 IDH1 (1.00) CA1CA2CA4CA6IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9567433-B2 Methods for forming a polycarbonate with a hydrophilic surface GM Global Technology Operations LLC (US) 2017-02-14 US disclosed
US-20160264729-A1 METHODS FOR FORMING A POLYCARBONATE WITH A HYDROPHILIC SURFACE GM GLOBAL TECHNOLOGY OPERATIONS LLC. 2016-09-15 US disclosed