SCHEMBL1584791

SCHEMBL1584791

Oc1ccc(Cc2ccccc2)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IDH1 O75874 1/20 1.00
▸ CA1 P00915 1/20 0.77
▸ CA2 P00918 1/20 0.77
▸ CA4 P22748 1/20 0.77
▸ CA6 P23280 1/20 0.77
▸ IGF1R P08069 2/20 0.64
▸ ALOX15 P16050 2/20 0.64
▸ HNF4A P41235 1/20 0.63
▸ BCL2 P10415 1/20 0.61
▸ BCL2L1 Q07817 1/20 0.61
▸ MAPT P10636 2/20 0.57
▸ MPO P05164 1/20 0.56
▸ CALM1 P0DP23 1/20 0.55
▸ HRAS P01112 1/20 0.53
▸ TRPA1 O75762 1/20 0.52
▸ KDM4E B2RXH2 1/20 0.52
▸ RGS12 O14924 1/20 0.52
▸ LMNA P02545 1/20 0.52
▸ POLB P06746 1/20 0.52
▸ GAA P10253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15387263 0.91 IDH1 (0.83) IDH1CA1CA2CA4CA6
SCHEMBL109054 0.91 CA1 (0.94) IDH1CA1CA2CA4CA6
SCHEMBL107211 0.88 CA1 (0.81) IDH1CA1CA2CA4CA6
SCHEMBL108093 0.88 CA1 (1.00) IDH1CA1CA2CA4CA6
SCHEMBL9645919 0.85 IDH1 (0.74) IDH1CA1CA2CA4CA6
SCHEMBL278268 0.84 CA1 (0.81) IDH1CA1CA2CA4CA6
SCHEMBL15722470 0.83 CA1 (0.90) IDH1CA1CA2CA4CA6
SCHEMBL9173452 0.83 IDH1 (0.70) IDH1CA1CA2CA4CA6
SCHEMBL10886054 0.83 IDH1 (0.70) IDH1CA1CA2CA4CA6
SCHEMBL8759223 0.83 IDH1 (0.70) IDH1CA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10202474-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2019-02-12 — — US claimed
US-20170073443-A1 PROCESS FOR PRODUCING POLYDIENES BRIDGESTONE CORPORATION (US) 2017-03-16 — — US claimed
EP-1511710-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES SUCH AS ALZHEIMER S DISEASE, TYPE 2 DIABETES, AND PARKINSON S DISEASE Proteotech, Inc. (US) 2005-03-09 — — EP claimed
WO-2003101927-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES SUCH AS ALZHEIMER'S DISEASE, TYPE 2 DIABETES, AND PARKINSON'S DISEASE PROTEOTECH, INC. (US) 2003-12-11 — — WO claimed
US-4221858-A EXPOSURE, SILVER HALIDE EMULSIONS, TANNING FUJI PHOTO FILM CO., LTD. (JP) 1980-09-09 — — US claimed
EP-3790855-B1 METHOD FOR ISOLATION OF AN AROMATIC DIANHYDRIDE AND AROMATIC DIANHYDRIDES PREPARED BY THE METHOD SHPP GLOBAL TECH BV (NL) 2024-06-19 — — EP disclosed
EP-3793983-B1 METHOD FOR ISOLATION OF A DIANHYDRIDE AND DIANHYDRIDES PREPARED BY THE METHOD SHPP GLOBAL TECH BV (NL) 2024-03-27 — — EP disclosed
US-11912689-B2 Method for isolation of an aromatic dianhydride and aromatic dianhydrides prepared by the method SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-02-27 — — US disclosed
WO-2024003821-A1 3,3'-AROMATIC BIS(ETHER IMIDE)S, POLYETHERIMIDES THEREOF AND METHODS FOR MAKING SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-01-04 — — WO disclosed
US-11787776-B2 Method for producing an aromatic dianhydride SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-10-17 — — US disclosed
US-11661416-B2 Method for isolation of a dianhydride and dianhydrides prepared by the method SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-05-30 — — US disclosed
US-20230111779-A1 METHODS OF MANUFACTURE OF DIANHYDRIDES CHAULAGAIN MANI RAJ (US) 2023-04-13 — — US disclosed
EP-0611764-A1 Method of preparing aromatic ether bisimides GENERAL ELECTRIC COMPANY (US) 1994-08-24 — — EP disclosed
US-5212277-A Engineering plastics KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1993-05-18 — — US disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 — — US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 — — EP disclosed
US-4233393-A PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1980-11-11 — — US disclosed
US-4221858-A EXPOSURE, SILVER HALIDE EMULSIONS, TANNING FUJI PHOTO FILM CO., LTD. (JP) 1980-09-09 — — US disclosed
US-4173477-A SILVER HALIDE; ALUMINUM SUPPORT, ANODIZED ALUMINUM OXIDE LAYER, 4-PHENYLCATECHOL; LITHOGRAPHIC PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1979-11-06 — — US disclosed
US-4101323-A Radiation-sensitive copying composition HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11787776-B2 Method for producing an aromatic dianhydride DDC, PAH, APEH IDH1 124/4885CA1 22/4885CA2 6/4885
US-11661416-B2 Method for isolation of a dianhydride and dianhydrides prepared by the method DDC, APEH, DNPEP IDH1 54/4885CA1 29/4885CA2 8/4885
US-20230111779-A1 METHODS OF MANUFACTURE OF DIANHYDRIDES H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NISCH, HDHD5 IDH1 27/4885CA1 63/4885CA2 303/4885
US-11912689-B2 Method for isolation of an aromatic dianhydride and aromatic dianhydrides prepared by the method DDC, APEH, PAH IDH1 44/4885CA1 104/4885CA2 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback