Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 16/20 | 0.80 |
| ▸ | HRH1 | P35367 | 15/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.56 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569519 | 0.89 | CCR3 (1.00) | CCR3HRH1KCNH2HRH3L3MBTL3 | |
| SCHEMBL6568389 | 0.85 | CCR3 (0.65) | CCR3HRH1KCNH2MBTD1L3MBTL3 | |
| SCHEMBL6569067 | 0.82 | CCR3 (0.62) | CCR3HRH1KCNH2HRH3MBTD1 | |
| SCHEMBL5416889 | 0.80 | HRH1 (0.90) | CCR3HRH1KCNH2 | |
| SCHEMBL5406031 | 0.80 | HRH1 (1.00) | CCR3HRH1KCNH2 | |
| SCHEMBL6569293 | 0.80 | CCR3 (0.65) | CCR3HRH1KCNH2L3MBTL3L3MBTL1 | |
| SCHEMBL5414525 | 0.79 | HRH1 (0.87) | CCR3HRH1KCNH2 | |
| SCHEMBL6568423 | 0.79 | CCR3 (0.63) | CCR3HRH1KCNH2MBTD1L3MBTL3 | |
| SCHEMBL5424883 | 0.79 | HRH1 (0.86) | CCR3HRH1KCNH2 | |
| SCHEMBL5403866 | 0.78 | HRH1 (0.80) | CCR3HRH1KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912941-B1 | PIPERIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2012-11-14 | — | — | EP | disclosed |
| EP-2402316-A1 | Piperidine derivatives | AstraZeneca AB (Publ) (SE) | 2012-01-04 | — | — | EP | disclosed |
| EP-1994002-A1 | PIPERIDINE DERIVATIVES, THEIR PROCESS FOR PREPARATION, THEIR USE AS THERAPEUTIC AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AstraZeneca AB (SE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007102767-A1 | PIPERIDINE DERIVATIVES, THEIR PROCESS FOR PREPARATION, THEIR USE AS THERAPEUTIC AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 2007-09-13 | — | — | WO | disclosed |