Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 12/20 | 0.63 |
| ▸ | HRH1 | P35367 | 10/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.44 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.44 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569067 | 0.90 | CCR3 (0.62) | CCR3HRH1KCNH2L3MBTL3L3MBTL1 | |
| SCHEMBL6570409 | 0.85 | CCR3 (0.57) | CCR3HRH1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL5409347 | 0.83 | HRH1 (0.70) | CCR3HRH1KCNH2 | |
| SCHEMBL6568389 | 0.80 | CCR3 (0.65) | CCR3HRH1KCNH2L3MBTL3L3MBTL1 | |
| SCHEMBL6568364 | 0.79 | CCR3 (0.64) | CCR3HRH1KCNH2L3MBTL3L3MBTL1 | |
| SCHEMBL180485 | 0.79 | CCR3 (0.80) | CCR3HRH1KCNH2L3MBTL3L3MBTL1 | |
| SCHEMBL5409191 | 0.78 | CCR3 (0.81) | CCR3HRH1KCNH2 | |
| SCHEMBL6567690 | 0.76 | CCR3 (0.63) | CCR3HRH1KCNH2L3MBTL3L3MBTL1 | |
| SCHEMBL5417002 | 0.74 | CCR3 (0.45) | CCR3HRH1KCNH2 | |
| SCHEMBL6569293 | 0.74 | CCR3 (0.65) | CCR3HRH1KCNH2L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404667-A1 | PIPERIDINE DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003004487-A1 | PIPERIDINE DERIVATIVES USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2003-01-16 | — | — | WO | disclosed |