Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17711573 | 0.85 | HDAC8 (0.43) | TDP1ALDH1A1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL29460268 | 0.83 | TDP1 (0.50) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL1454745 | 0.80 | TDP1 (0.43) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL14541275 | 0.78 | TDP1 (0.50) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL19265914 | 0.77 | TDP1 (0.54) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL1454381 | 0.77 | TDP1 (0.54) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL5195722 | 0.76 | TDP1 (0.43) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL9572748 | 0.75 | TDP1 (0.46) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL4167974 | 0.75 | TDP1 (0.46) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL17710423 | 0.75 | TDP1 (0.52) | TDP1ALDH1A1TSHRCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124206-A1 | METAL COMPLEXES, METHODS OF MAKING THE SAME, AND USES THEREOF | UNIVERSITY OF MANITOBA (CA) | 2020-06-25 | — | — | WO | disclosed |
| EP-3328870-A1 | NITROGEN TITANIUM COMPLEX, CATALYTIC SYSTEM COMPRISING SAID NITROGEN TITANIUM COMPLEX AND PROCESS FOR THE (CO)POLYMERIZATION OF CONJUGATED DIENES | Versalis S.p.A. (IT) | 2018-06-06 | — | — | EP | disclosed |
| EP-3194409-A1 | PYRIDINE COMPLEX OF ZIRCONIUM, CATALYTIC SYSTEM COMPRISING SAID PYRIDINE COMPLEX OF ZIRCONIUM AND PROCESS OF (CO)POLYMERIZATION OF CONJUGATED DIENES | Versalis S.p.A. (IT) | 2017-07-26 | — | — | EP | disclosed |
| WO-2017017203-A1 | NITROGEN TITANIUM COMPLEX, CATALYTIC SYSTEM COMPRISING SAID NITROGEN TITANIUM COMPLEX AND PROCESS FOR THE (CO)POLYMERIZATION OF CONJUGATED DIENES | VERSALIS S.P.A. (IT) | 2017-02-02 | — | — | WO | disclosed |
| WO-2016042014-A1 | PYRIDINE COMPLEX OF ZIRCONIUM, CATALYTIC SYSTEM COMPRISING SAID PYRIDINE COMPLEX OF ZIRCONIUM AND PROCESS OF (CO)POLYMERIZATION OF CONJUGATED DIENES | VERSALIS S.P.A. (IT) | 2016-03-24 | — | — | WO | disclosed |
| EP-2496579-A1 | 1-SUBSTITUTED 2-AZABICYCLO [3.1.1]HEPTYL DERIVATIVES USEFUL AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS FOR TREATING NEUROLOGIC DISORDERS | Universiteit Gent (BE) | 2012-09-12 | — | — | EP | disclosed |
| EP-2376593-A2 | PHOTOACTIVE COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION | E. I. du Pont de Nemours and Company (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2011054885-A1 | 1-SUBSTITUTED 2-AZABICYCLO [3.1.1] HEPTYL DERIVATIVES USEFUL AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS FOR TREATING NEUROLOGIC DISORDERS | UNIVERSITEIT GENT (BE) | 2011-05-12 | — | — | WO | disclosed |
| WO-2011055142-A2 | 1,4-QUINONES AND THEIR SULFUR ANALOGUES USEFUL AS LIGANDS OF N-ACETYLTRANSFERASES | ISIS INNOVATION LIMITED (GB) | 2011-05-12 | — | — | WO | disclosed |
| WO-2010068865-A2 | PHOTOACTIVE COMPOSITION AND ELECTRONIC DEVICE MADE WITH THE COMPOSITION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-17 | — | — | WO | disclosed |
| EP-1773895-A2 | CATALYSTS FOR OLEFIN POLYMERIZATION OR OLIGOMERIZATION | E.I.Du pont de nemours and company (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006010065-A2 | CATALYSTS FOR OLEFIN POLYMERIZATION OR OLIGOMERIZATION | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-01-26 | — | — | WO | disclosed |