Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29460268 | 0.79 | TDP1 (0.50) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL1804931 | 0.76 | TDP1 (0.46) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL27914667 | 0.76 | MAPT (0.47) | TDP1CYP3A4LMNATHRBL3MBTL1 | |
| SCHEMBL17711573 | 0.70 | HDAC8 (0.43) | TDP1ALDH1A1MAPK1HTTMAPT | |
| SCHEMBL12231496 | 0.69 | GRIN1 (0.57) | TDP1CYP3A4LMNAL3MBTL1HIF1A | |
| SCHEMBL21637581 | 0.68 | TDP1 (0.64) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL8346697 | 0.67 | MAPT (0.56) | TDP1ALDH1A1TSHRCYP3A4LMNA | |
| SCHEMBL28255718 | 0.67 | TDP1 (0.45) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL2020475 | 0.67 | TDP1 (0.55) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL2495982 | 0.66 | TDP1 (0.54) | TDP1ALDH1A1TSHRCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812242-A1 | SHEET PRODUCT FOR THERMAL PRINTING AND FOR MAGNETIC RECORDING | Arjo Wiggins Limited (GB) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006043044-A1 | SHEET PRODUCT FOR THERMAL PRINTING AND FOR MAGNETIC RECORDING | ARJO WIGGINS LIMITED (GB) | 2006-04-27 | — | — | WO | disclosed |