Sinapultide

Sinapultide

SCHEMBL180504

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 5/20 0.53
NPY1R P25929 4/20 0.53
NPY2R P49146 3/20 0.53
ERAP2 Q6P179 1/20 0.49
ERAP1 Q9NZ08 1/20 0.49
LNPEP Q9UIQ6 1/20 0.49
CPB2 Q96IY4 7/20 0.47
FOLH1 Q04609 1/20 0.47
OPRK1 P41145 1/20 0.46
GSR P00390 1/20 0.46
NPY5R Q15761 2/20 0.46
DPP8 Q6V1X1 1/20 0.45
DPP9 Q86TI2 1/20 0.45
DPP7 Q9UHL4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31343363 1.00 NPY4R (0.53) NPY4RNPY1RNPY2RERAP2ERAP1
SCHEMBL31343405 1.00 NPY4R (0.53) NPY4RNPY1RNPY2RERAP2ERAP1
SCHEMBL31343323 1.00 NPY4R (0.53) NPY4RNPY1RNPY2RERAP2ERAP1
Sinapultide SCHEMBL29360133 1.00 NPY4R (0.53) NPY4RNPY1RNPY2RERAP2ERAP1
SCHEMBL31343172 0.99 NPY4R (0.52) NPY4RNPY1RNPY2RERAP2ERAP1
SCHEMBL29404079 0.99 NPY4R (0.52) NPY4RNPY1RNPY2RERAP2ERAP1
SCHEMBL29630471 0.97 NPY4R (0.53) NPY4RNPY1RNPY2RERAP2ERAP1
SCHEMBL29682467 0.96 NPY4R (0.52) NPY4RNPY1RNPY2RERAP2ERAP1
SCHEMBL31018772 0.95 NPY4R (0.50) NPY4RNPY1RNPY2RERAP2ERAP1
SCHEMBL31018773 0.95 NPY4R (0.50) NPY4RNPY1RNPY2RERAP2ERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3727418-B1 SURFACTANT FORMULATIONS FOR INHALATION MERZ PHARMACEUTICALS LLC (US) 2026-04-08 EP claimed
US-12589161-B2 PEGylated synthetic KL4 peptide, compositions and methods thereof THE UNIVERSITY OF HONG KONG (CN) 2026-03-31 US claimed
US-20250288516-A1 Surfactant Formulations for Inhalation MERZ PHARMACEUTICALS LLC (US) 2025-09-18 US claimed
US-20250262150-A1 Surfactant Formulations for Inhalation MERZ PHARMACEUTICALS LLC (US) 2025-08-21 US claimed
CN-120000688-A Atomization inhalation composition based on stem extracellular vesicles, and preparation method and application thereof 山东杰凯生物科技有限公司 2025-05-16 CN claimed
EP-3996686-B1 PEGYLATED SYNTHETIC KL4 PEPTIDE, COMPOSITIONS AND METHODS THEREOF UNIV HONG KONG (CN) 2025-03-26 EP claimed
CN-114206906-B PEGylated synthetic KL4 peptides, compositions and methods thereof 香港大学 2024-02-20 CN claimed
US-20230172869-A1 A NANO-ENABLED VACCINATION APPROACH FOR CORONAVIRUS DISEASE (COVID-19) AND OTHER VIRAL DISEASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-06-08 US claimed
CN-114213546-B VEGFR-targeted cleavage peptide conjugate and application thereof 华中科技大学同济医学院附属协和医院 2023-05-05 CN claimed
EP-4138856-A1 A NANO-ENABLED VACCINATION APPROACH FOR CORONAVIRUS DISEASE (COVID-19) AND OTHER VIRAL DISEASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-03-01 EP claimed
EP-1638567-A1 COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE5 INHIBITOR FOR THE TREATMENT OF LUNG DISEASES ALTANA Pharma AG (DE) 2006-03-29 EP claimed
WO-2006013183-A1 COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A TNF-DERIVED PEPTIDE ALTANA PHARMA AG (DE) 2006-02-09 WO claimed
WO-2005021037-A1 COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE2 INHIBITOR ALTANA PHARMA AG (DE) 2005-03-10 WO claimed
EP-1357928-A4 A NOVEL PHARMACEUTICAL COMPOUND AND METHODS OF MAKING AND USING SAME NEW RIVER PHARMACEUTICALS INC (US) 2004-12-29 EP claimed
WO-2004110450-A1 COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE5 INHIBITOR FOR THE TREATMENT OF LUNG DISEASES ALTANA PHARMA AG (DE) 2004-12-23 WO claimed
US-20040132967-A1 Mimetic peptide comprised of terminal amino acid sequences of surfactant protein b (SP-B) and dipalmitoylphosphatidylcholine for use in treatment of respiratory system disorder WALTHER FRANS J (US) 2004-07-08 US claimed
EP-1357928-A2 A NOVEL PHARMACEUTICAL COMPOUND AND METHODS OF MAKING AND USING SAME New River Pharmaceuticals Inc. (US) 2003-11-05 EP claimed
WO-2003020200-A2 A NOVEL PHARMACEUTICAL COMPOUND AND METHODS OF MAKING AND USING SAME NEW RIVER PHARMACEUTICALS INC. (US) 2003-03-13 WO claimed
US-6436970-B1 POWDERS COMPRISING HETEROCYCLIC IMINES, PROTEIN-B AND/OR-C, USED FOR THE PROPHYLAXIS OF INFANT OR ADULT RESPIRATORY DISTRESS SYNDROME BYK GULDEN LOMBERG CHEMISCHE FEBRIK GMBH (DE) 2002-08-20 US claimed
US-6031075-A AMINO ACID SEQUENCE OF SYNTHESIZED ISOLATED ALVEOLAR SURFACTANT PROTEIN-B PRODUCED BY CLEAVING FUSION PROTEIN CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2000-02-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12589161-B2 PEGylated synthetic KL4 peptide, compositions and methods thereof KLK14, KLK4, KLK13 NPY4R 56/4885NPY1R 445/4885NPY2R 518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.