SCHEMBL18050810

SCHEMBL18050810

CCN(CC)C(=O)Oc1ccc(C)cc1C(=O)N(CC)CC

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
LMNA P02545 6/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
TSHR P16473 1/20 0.47
HPGD P15428 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAOB P27338 2/20 0.45
MAOA P21397 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
NPC1 O15118 1/20 0.45
MAPT P10636 1/20 0.45
RAB9A P51151 1/20 0.45
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18050812 0.85 MAOB (0.46) MEN1KMT2ALMNAL3MBTL1TSHR
SCHEMBL22372572 0.83 MEN1 (0.50) MEN1KMT2ALMNAL3MBTL1TSHR
SCHEMBL22372586 0.83 LMNA (0.58) MEN1KMT2ALMNAL3MBTL1TSHR
SCHEMBL13368630 0.83 MEN1 (0.53) MEN1KMT2ALMNAL3MBTL1TSHR
SCHEMBL18050806 0.81 HSP90AA1 (0.63) MEN1KMT2ALMNAL3MBTL1TSHR
SCHEMBL18050799 0.80 HSD17B10 (0.59) MEN1KMT2ALMNAL3MBTL1TSHR
SCHEMBL509140 0.77 HPGD (0.54) MEN1KMT2ALMNATSHRHPGD
SCHEMBL879089 0.77 MEN1 (0.50) MEN1KMT2ALMNAL3MBTL1TSHR
SCHEMBL17113681 0.77 MEN1 (0.46) MEN1KMT2ALMNAL3MBTL1TSHR
SCHEMBL17113693 0.77 MEN1 (0.46) MEN1KMT2ALMNAL3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3268396-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2019-04-17 EP disclosed
US-10017590-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-07-10 US disclosed
US-20180057620-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-03-01 US disclosed
EP-3268396-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2018-01-17 EP disclosed
WO-2016142334-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2016-09-15 WO disclosed