Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050781 | 0.88 | HSD17B10 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL18050733 | 0.87 | HSD17B10 (0.52) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL18050796 | 0.86 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL19895661 | 0.86 | HSD17B10 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL18050795 | 0.85 | HSD17B10 (0.54) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL10013764 | 0.84 | CYP1A2 (0.78) | CYP1A2CYP3A4CYP2D6CYP2C19TSHR | |
| SCHEMBL29728640 | 0.83 | HSD17B10 (0.70) | HSD17B10TSHRLMNAL3MBTL1MEN1 | |
| SCHEMBL16965616 | 0.83 | HSD17B10 (0.70) | HSD17B10TSHRLMNAL3MBTL1MEN1 | |
| SCHEMBL18050768 | 0.81 | HSD17B10 (0.50) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL16965294 | 0.81 | HSD17B10 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268396-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-04-17 | — | — | EP | disclosed |
| US-10017590-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-07-10 | — | — | US | disclosed |
| US-20180057620-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-03-01 | — | — | US | disclosed |
| EP-3268396-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2018-01-17 | — | — | EP | disclosed |
| WO-2016142334-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-09-15 | — | — | WO | disclosed |