Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | TSPO | P30536 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050816 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP2D6CYP2C19CYP3A4TSHR | |
| SCHEMBL8567854 | 0.83 | TSHR (0.60) | CYP1A2CYP2D6CYP2C19CYP3A4TSHR | |
| SCHEMBL18050796 | 0.83 | CYP1A2 (0.57) | CYP1A2CYP2D6CYP2C19CYP3A4TSHR | |
| SCHEMBL13226266 | 0.79 | CYP1A2 (0.56) | CYP1A2CYP2D6CYP2C19CYP3A4TSHR | |
| SCHEMBL13206752 | 0.79 | TSHR (0.56) | CYP1A2CYP2D6CYP2C19CYP3A4TSHR | |
| SCHEMBL28118170 | 0.78 | ATM (0.58) | CYP1A2CYP2D6CYP2C19CYP3A4TSHR | |
| SCHEMBL1792326 | 0.78 | TSHR (0.55) | CYP1A2CYP2D6CYP2C19CYP3A4TSHR | |
| SCHEMBL4556502 | 0.78 | TSHR (0.55) | CYP1A2CYP2D6CYP2C19CYP3A4TSHR | |
| SCHEMBL17276760 | 0.78 | TSPO (0.59) | CYP1A2CYP2D6CYP2C19CYP3A4TSHR | |
| SCHEMBL2550830 | 0.77 | AKR1B1 (0.57) | CYP1A2CYP2D6CYP2C19CYP3A4TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168833-B2 | Schwartz reagents: methods of in situ generation and use | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-05-01 | — | — | US | disclosed |
| US-20100145060-A1 | Schwartz Reagents: Methods of In Situ Generation and Use | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2010-06-10 | — | — | US | disclosed |
| US-4305717-A | P-PHENYLENEDIAMINE OXIDIZING BASE AND COUPLER TO FORM INDAMINES | L'OREAL (FR) | 1981-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145060-A1 | Schwartz Reagents: Methods of In Situ Generation and Use | CBR3, CBR1, ZFR | CYP1A2 597/4885CYP2D6 3048/4885CYP2C19 2203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.