Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398862 | 0.85 | HTR2A (0.48) | HTR2ASIGMAR1POLBCALM1BCL2 | |
| SCHEMBL355039 | 0.83 | HTR2A (0.47) | HTR2ASIGMAR1POLBCALM1BCL2 | |
| SCHEMBL7735333 | 0.82 | CALM1 (0.55) | HTR2ACALM1BCL2BCL2L1HPGD | |
| SCHEMBL583540 | 0.81 | HTR2A (0.71) | HTR2AHPGDSMN1; SMN2LOXL2 | |
| SCHEMBL542553 | 0.80 | HTR2A (0.56) | HTR2ASIGMAR1POLBCALM1BCL2 | |
| SCHEMBL88596 | 0.78 | MAOB (0.56) | HTR2ASIGMAR1POLBHPGDSMN1; SMN2 | |
| SCHEMBL10360527 | 0.78 | HTR2A (0.54) | HTR2ACALM1BCL2BCL2L1HPGD | |
| SCHEMBL16267990 | 0.77 | HTR2A (0.53) | HTR2ACALM1BCL2BCL2L1HPGD | |
| Hydrochloric Acid SCHEMBL8746158 | 0.77 | MAOB (0.58) | HTR2ASIGMAR1POLBHPGDSMN1; SMN2 | |
| SCHEMBL6557214 | 0.76 | CALM1 (0.52) | HTR2APOLBCALM1SMN1; SMN2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016141458-A1 | BISPHENOL ETHER DERIVATIVES AND METHODS FOR USING THE SAME | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2016-09-15 | — | — | WO | disclosed |