Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB4 | P54760 | 5/20 | 0.50 |
| ▸ | TEK | Q02763 | 4/20 | 0.50 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1809498 | 0.89 | EPHB4 (0.43) | EPHB4TEKKDRMAOBMEN1 | |
| SCHEMBL1813493 | 0.89 | MAOB (0.45) | EPHB4TEKKDRMAOBCYP19A1 | |
| SCHEMBL1812905 | 0.89 | EPHB4 (0.48) | EPHB4TEKKDRCYP19A1NPC1 | |
| SCHEMBL1806942 | 0.88 | CYP19A1 (0.45) | EPHB4TEKKDRCYP19A1NPC1 | |
| SCHEMBL1806051 | 0.87 | EPHB4 (0.45) | EPHB4TEKKDRMAOBCYP19A1 | |
| SCHEMBL1734185 | 0.86 | CYP19A1 (0.51) | EPHB4TEKKDRCYP19A1MEN1 | |
| SCHEMBL1807224 | 0.86 | CYP19A1 (0.47) | EPHB4KDRCYP19A1NPC1RAB9A | |
| SCHEMBL1808810 | 0.86 | TEK (0.45) | EPHB4TEKKDRMAOBCYP19A1 | |
| SCHEMBL1814458 | 0.85 | CYP19A1 (0.40) | EPHB4TEKKDRCYP19A1NPC1 | |
| SCHEMBL1816497 | 0.83 | TEK (0.43) | EPHB4TEKKDRCYP19A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051198-A2 | PYRIDINE DERIVATIVES AS AGRICULTURAL PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051198-A2 | PYRIDINE DERIVATIVES AS AGRICULTURAL PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | WO | disclosed |