Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB4 | P54760 | 5/20 | 0.43 |
| ▸ | TEK | Q02763 | 5/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1805403 | 0.89 | EPHB4 (0.50) | EPHB4TEKKDRMEN1KMT2A | |
| SCHEMBL1806051 | 0.88 | EPHB4 (0.45) | EPHB4TEKKDRMAPTMAOB | |
| SCHEMBL1809770 | 0.87 | MAOB (0.48) | EPHB4TEKKDRMAOB | |
| SCHEMBL1808810 | 0.85 | TEK (0.45) | EPHB4TEKKDRMEN1KMT2A | |
| SCHEMBL1812905 | 0.84 | EPHB4 (0.48) | EPHB4TEKKDRKDM4EMEN1 | |
| SCHEMBL1813493 | 0.82 | MAOB (0.45) | EPHB4TEKKDRTP53MAPT | |
| SCHEMBL1808185 | 0.82 | CYP19A1 (0.44) | EPHB4TEKKDRMEN1KMT2A | |
| SCHEMBL1807224 | 0.82 | CYP19A1 (0.47) | EPHB4KDRMEN1KMT2ACCNK | |
| SCHEMBL1734185 | 0.82 | CYP19A1 (0.51) | EPHB4TEKKDRMEN1KMT2A | |
| SCHEMBL1806942 | 0.82 | CYP19A1 (0.45) | EPHB4TEKKDRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051198-A2 | PYRIDINE DERIVATIVES AS AGRICULTURAL PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051198-A2 | PYRIDINE DERIVATIVES AS AGRICULTURAL PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | WO | disclosed |