Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | FABP1 | P07148 | 1/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18056778 | 0.94 | MAPK1 (0.55) | SMN1; SMN2NPC1RAB9AKDM4ETP53 | |
| SCHEMBL9885179 | 0.89 | MCL1 (0.49) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL13579197 | 0.86 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL15293401 | 0.86 | NPC1 (0.54) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL17914310 | 0.86 | HDAC8 (0.50) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL18074858 | 0.86 | TDP1 (0.52) | SMN1; SMN2NPC1RAB9AMAPTKDM4E | |
| SCHEMBL17268315 | 0.83 | TDP1 (0.50) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL9885177 | 0.82 | MAPK1 (0.57) | NPC1RAB9ATSHRMEN1KMT2A | |
| SCHEMBL18415715 | 0.81 | PLAU (0.54) | SMN1; SMN2NPC1RAB9ATSHRMEN1 | |
| SCHEMBL18517741 | 0.81 | NPC1 (0.61) | SMN1; SMN2NPC1RAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180001544-A1 | Method for Solid Freeform Fabrication | RICOH COMPANY, LTD. (JP) | 2018-01-04 | — | — | US | disclosed |
| US-9808993-B2 | Method for solid freeform fabrication | RICOH CO., LTD. (JP) | 2017-11-07 | — | — | US | disclosed |
| US-20170260328-A1 | Methods for Solid Freeform Fabrication | RICOH CO., LTD. (JP) | 2017-09-14 | — | — | US | disclosed |
| US-9695280-B2 | Methods for solid freeform fabrication | RICOH CO., LTD. (JP) | 2017-07-04 | — | — | US | disclosed |
| US-20160257843-A1 | Method for Solid Freeform Fabrication | RICOH CO., LTD. (JP) | 2016-09-08 | — | — | US | disclosed |
| US-20160257067-A1 | Methods for Solid Freeform Fabrication | RICOH CO., LTD. (JP) | 2016-09-08 | — | — | US | disclosed |
| US-20160257783-A1 | Methods for Solid Freeform Fabrication | RICOH CO., LTD. (JP) | 2016-09-08 | — | — | US | disclosed |
| US-20160257070-A1 | Method for Solid Freeform Fabrication | RICOH CO., LTD. (JP) | 2016-09-08 | — | — | US | disclosed |