SCHEMBL180582

SCHEMBL180582

Nc1c(O)cccc1C(=O)CC(N)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 1.00
HIF1A Q16665 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
G6PD P11413 1/20 0.56
CASP7 P55210 1/20 0.56
CASP6 P55212 1/20 0.56
KMO O15229 3/20 0.43
KYNU Q16719 1/20 0.41
PTGS1 P23219 2/20 0.40
SLC7A5 Q01650 2/20 0.40
ALPI P09923 1/20 0.40
PKM P14618 1/20 0.40
XIAP P98170 1/20 0.40
CASR P41180 1/20 0.39
SLC1A3 P43003 2/20 0.38
SLC1A2 P43004 2/20 0.38
SLC1A1 P43005 2/20 0.38
GRM2 Q14416 1/20 0.38
GRM3 Q14832 1/20 0.38
USP2 O75604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29934345 1.00 KDM4E (1.00) KDM4EHIF1ATDP1G6PDCASP7
SCHEMBL16616577 1.00 KDM4E (1.00) KDM4EHIF1ATDP1G6PDCASP7
SCHEMBL17641540 1.00 KDM4E (1.00) KDM4EHIF1ATDP1G6PDCASP7
SCHEMBL30973707 1.00 KDM4E (1.00) KDM4EHIF1ATDP1G6PDCASP7
SCHEMBL134058 1.00 KDM4E (1.00) KDM4EHIF1ATDP1G6PDCASP7
SCHEMBL29375641 1.00 KDM4E (1.00) KDM4EHIF1ATDP1G6PDCASP7
SCHEMBL29352838 1.00 KDM4E (1.00) KDM4EHIF1ATDP1G6PDCASP7
Water SCHEMBL8081334 0.98 KDM4E (0.97) KDM4EHIF1ATDP1G6PDCASP7
Kynurenine SCHEMBL6932225 0.87 KDM4E (0.77) KDM4EHIF1ATDP1G6PDCASP7
SCHEMBL19260994 0.86 KDM4E (0.75) KDM4EHIF1ATDP1G6PDCASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2275 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098007-A1 Compounds and Their Use in Filtering Ultraviolet and/or High-Energy Visible Light SOLIOME INC (US) 2026-04-09 US claimed
US-12551459-B2 Combination of kynurenine and antigen presenting cells (APC) as therapeutics and methods for their use in immune modulation THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2026-02-17 US claimed
EP-4648788-A1 LIPID BINDING PROTEIN MOLECULE THERAPY Abionyx Pharma SA (FR) 2025-11-19 EP claimed
US-20250255792-A1 Methods of Using a Small Molecule Chemical Compound to Reduce the Appearance of Rhytids and Wrinkles BIRCHBIOMED INC. (CA) 2025-08-14 US claimed
EP-4587007-A2 COMPOUNDS AND THEIR USE IN FILTERING ULTRAVIOLET AND/OR HIGH-ENERGY VISIBLE LIGHT Soliome, Inc. (US) 2025-07-23 EP claimed
EP-4572737-A1 METHODS OF USING A SMALL MOLECULE CHEMICAL COMPOUND TO REDUCE THE APPEARANCE OF RHYTIDS AND WRINKLES Birchbiomed Inc. (CA) 2025-06-25 EP claimed
EP-4551232-A1 METABOLOMIC IMPROVEMENTS USING RESISTANT STARCH SUPPLEMENTATION Mcpharma Biotech Inc. (CA) 2025-05-14 EP claimed
CN-119894495-A Method for reducing wrinkle and crease appearance using small molecule compounds 伯奇生物医药有限公司 2025-04-25 CN claimed
EP-4535004-A1 METHOD FOR ASSISTING DIAGNOSIS OF BLOOD TUMOR, METHOD FOR OBTAINING DATA FOR DIAGNOSING BLOOD TUMOR, AND KIT FOR SAID METHODS FUJIFILM Corporation (JP) 2025-04-09 EP claimed
WO-2025068213-A1 USE OF A MARKER SET FOR DETERMINING THE RISK OF HAVING OR DEVELOPING BLADDER CANCER NUMARES AG (DE) 2025-04-03 WO claimed
EP-1093580-A1 DIAGNOSIS OF PREDISPOSITION TO EPILEPSY AND MONITORING OF ANTIEPILEPTIC TREATMENT Advanced Neuroprotective Systems Ltd. (IL) 2001-04-25 EP claimed
WO-2001001963-A1 A METHOD FOR THE IMPROVEMENT OF TRANSPORT ACROSS ADAPTABLE SEMI-PERMEABLE BARRIERS IDEA AG (DE) 2001-01-11 WO claimed
WO-2001001962-A1 A METHOD FOR THE IMPROVEMENT OF TRANSPORT ACROSS ADAPTABLE SEMI-PERMEABLE BARRIERS IDEA AG. (DE) 2001-01-11 WO claimed
CN-1275060-A Liver function test NORGINE LTD (GB) 2000-11-29 CN claimed
EP-1003458-A2 LIVER FUNCTION TEST Norgine Limited (GB) 2000-05-31 EP claimed
US-6030841-A PROCESSING SERIES OF BLOOD SAMPLES OBTAINED AT TIMED INTERVALS AFTER INTRAVENOUS INJECTION OF COLORED/FLUORESCENT BILE ACID DERIVATIVE TO OBTAIN PLASMA, MEASURING COLOR OR FLUORESCENCE, FITTING TO PLASMA ELIMINATION CURVE, COMPARING NORGINE LIMITED (GB) 2000-02-29 US claimed
WO-1999058968-A1 DIAGNOSIS OF PREDISPOSITION TO EPILEPSY AND MONITORING OF ANTIEPILEPTIC TREATMENT ADVANCED NEUROPROTECTIVE SYSTEMS LTD. (IL) 1999-11-18 WO claimed
WO-1999007325-A1 LIVER FUNCTION TEST NORGINE LIMITED (GB) 1999-02-18 WO claimed
EP-0844890-A1 THE USE OF BILE ACID DERIVATIVES THE UNIVERSITY OF BIRMINGHAM (GB) 1998-06-03 EP claimed
WO-1997006829-A1 THE USE OF BILE ACID DERIVATIVES THE UNIVERSITY OF BIRMINGHAM (GB) 1997-02-27 WO claimed