Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.38 |
| ▸ | CA1 | P00915 | 17/20 | 0.38 |
| ▸ | CA12 | O43570 | 12/20 | 0.38 |
| ▸ | CA9 | Q16790 | 9/20 | 0.38 |
| ▸ | CA4 | P22748 | 11/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10292810 | 0.94 | CA2 (0.42) | CA2CA1CA12CA9CA4 | |
| SCHEMBL2835718 | 0.89 | CA2 (0.41) | CA2CA1CA12CA9CA4 | |
| SCHEMBL15193658 | 0.88 | CA2 (0.39) | CA2CA1CA12CA9CA4 | |
| SCHEMBL16103763 | 0.88 | CA2 (0.40) | CA2CA1CA12CA9CA4 | |
| SCHEMBL13341514 | 0.85 | CA2 (0.41) | CA2CA1CA12CA9CA4 | |
| SCHEMBL10292507 | 0.85 | CA1 (0.41) | CA2CA1CA12CA9CA4 | |
| SCHEMBL15817506 | 0.84 | CA1 (0.46) | CA2CA1CA12CA9CA4 | |
| SCHEMBL15199010 | 0.82 | CA2 (0.42) | CA2CA1CA12CA9CA4 | |
| SCHEMBL18059016 | 0.81 | CA2 (0.41) | CA2CA1CA12CA9 | |
| SCHEMBL15194209 | 0.80 | CA1 (0.41) | CA2CA1CA12CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9433594-B2 | Technetium- and rhenium-bis(heteroaryl) complexes and methods of use thereof | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2016-09-06 | — | — | US | disclosed |