Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40143 | 0.90 | SLC34A2 (0.61) | SLC34A2MAPK14ROS1MLYCDROCK2 | |
| SCHEMBL18059173 | 0.88 | SLC34A2 (0.45) | SLC34A2MAPK14MLYCDGPR52ROCK2 | |
| SCHEMBL18059182 | 0.84 | SLC34A2 (0.55) | SLC34A2MAPK14MLYCDGPR52ROCK2 | |
| SCHEMBL40087 | 0.82 | SLC34A2 (0.61) | SLC34A2MAPK14MLYCDGPR52ROCK2 | |
| SCHEMBL46448 | 0.81 | SLC34A2 (0.69) | SLC34A2MAPK14ROS1MLYCDROCK2 | |
| SCHEMBL45407 | 0.80 | SLC34A2 (0.63) | SLC34A2MAPK14MLYCDROCK2ROCK1 | |
| SCHEMBL46451 | 0.80 | SLC34A2 (0.63) | SLC34A2MAPK14MLYCDROCK2ROCK1 | |
| SCHEMBL39846 | 0.78 | SLC34A2 (0.63) | SLC34A2MAPK14MLYCDGPR52ROCK2 | |
| SCHEMBL39854 | 0.78 | SLC34A2 (0.56) | SLC34A2MAPK14ROCK2ROCK1 | |
| SCHEMBL39957 | 0.78 | MAPK14 (0.50) | SLC34A2MAPK14ROS1MLYCDROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2591354-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2016-09-07 | — | — | EP | disclosed |