Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.49 |
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.38 |
| ▸ | BRAF | P15056 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15421013 | 0.91 | SLC34A2 (0.61) | SLC34A2GPR52BRAFHRH3ROCK2 | |
| SCHEMBL18059161 | 0.90 | KDM4C (0.42) | SLC34A2BRAFROCK2KDM4EMLYCD | |
| SCHEMBL39796 | 0.85 | SLC34A2 (0.67) | SLC34A2GPR52BRAFHRH3ROCK2 | |
| SCHEMBL46969 | 0.84 | SLC34A2 (0.54) | SLC34A2GPR52BRAFHRH3ROCK2 | |
| SCHEMBL15432716 | 0.83 | SLC34A2 (0.62) | SLC34A2BRAFROCK2ROCK1KDM4E | |
| SCHEMBL18059177 | 0.83 | SLC34A2 (0.46) | SLC34A2BRAFROCK2KDM4EMLYCD | |
| SCHEMBL16355205 | 0.82 | SLC34A2 (0.61) | SLC34A2BRAFROCK2ROCK1KDM4E | |
| SCHEMBL16355215 | 0.81 | SLC34A2 (0.70) | SLC34A2GPR52BRAFROCK2ROCK1 | |
| SCHEMBL15432766 | 0.81 | SLC34A2 (0.70) | SLC34A2GPR52BRAFROCK2ROCK1 | |
| SCHEMBL19580025 | 0.81 | SLC34A2 (0.75) | SLC34A2BRAFROCK2ROCK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2591354-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2016-09-07 | — | — | EP | disclosed |