Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | SLC34A2 | O95436 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 4/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18059177 | 0.93 | SLC34A2 (0.46) | KDM4CSLC34A2BRAFMLYCDMMP13 | |
| SCHEMBL18059162 | 0.90 | SLC34A2 (0.49) | SLC34A2BRAFMLYCDKDM4EROCK2 | |
| SCHEMBL39793 | 0.90 | SLC34A2 (0.52) | KDM4CSLC34A2BRAFMLYCDMMP13 | |
| SCHEMBL46796 | 0.90 | SLC34A2 (0.52) | KDM4CSLC34A2BRAFMLYCDMMP13 | |
| SCHEMBL47715 | 0.85 | SLC34A2 (0.52) | SLC34A2BRAFKDM4EROCK2RAF1 | |
| SCHEMBL19579980 | 0.84 | SLC34A2 (0.52) | KDM4CSLC34A2BRAFMLYCDMMP13 | |
| SCHEMBL19579944 | 0.83 | SLC34A2 (0.52) | KDM4CSLC34A2BRAFKDM4EROCK2 | |
| SCHEMBL46782 | 0.83 | SLC34A2 (0.51) | SLC34A2BRAFMLYCDKDM4EROCK2 | |
| SCHEMBL46797 | 0.83 | SLC34A2 (0.52) | SLC34A2BRAFKDM4EROCK2RAF1 | |
| SCHEMBL39722 | 0.82 | SLC34A2 (0.57) | KDM4CSLC34A2BRAFMLYCDMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2591354-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2016-09-07 | — | — | EP | disclosed |