Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 4/20 | 0.37 |
| ▸ | BRAF | P15056 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSPH1 | Q92598 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46481 | 0.89 | SLC34A2 (0.52) | SLC34A2BRAFMAPTNPSR1HSP90AA1 | |
| SCHEMBL46478 | 0.86 | SLC34A2 (0.50) | SLC34A2RAF1BRAFMAPTNPSR1 | |
| SCHEMBL19579996 | 0.86 | SLC34A2 (0.56) | SLC34A2RAF1BRAFMAPTNPSR1 | |
| SCHEMBL46763 | 0.86 | SLC34A2 (0.55) | SLC34A2RAF1BRAFMAPTNPSR1 | |
| SCHEMBL46430 | 0.85 | SLC34A2 (0.47) | SLC34A2RAF1BRAFMAPTNPSR1 | |
| SCHEMBL39856 | 0.85 | SLC34A2 (0.54) | SLC34A2RAF1BRAFMAPTALDH1A1 | |
| SCHEMBL6002055 | 0.85 | SLC34A2 (0.51) | SLC34A2RAF1BRAFMAPTNPSR1 | |
| SCHEMBL10274259 | 0.85 | SLC34A2 (0.51) | SLC34A2RAF1BRAFLCKKDR | |
| SCHEMBL45535 | 0.84 | SLC34A2 (0.64) | SLC34A2RAF1BRAFKDM4ELMNA | |
| SCHEMBL46486 | 0.84 | SLC34A2 (0.53) | SLC34A2RAF1BRAFMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2591354-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2016-09-07 | — | — | EP | disclosed |