SCHEMBL18059303

C=C1[C@H](CC(C)(C)[Si](C)(C)O)C/C(=C\C=C2/CCCC3(C)C2CCC3[C@@H](C)OC[C@H](C)C(C)(C)CC(C)(C)[Si](C)(C)O)C[C@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.57

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	VDR	P11473	6/20	0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18059309	0.88	VDR (0.49)	VDR
SCHEMBL19158370	0.86	VDR (0.49)	VDR
SCHEMBL14146430	0.86	VDR (0.49)	VDR
SCHEMBL13090106	0.86	VDR (0.49)	VDR
SCHEMBL18059319	0.86	VDR (0.49)	VDR
SCHEMBL12828196	0.86	VDR (0.48)	VDR
SCHEMBL14731531	0.86	VDR (0.48)	VDR
SCHEMBL14755286	0.86	VDR (0.48)	VDR
SCHEMBL9070736	0.85	VDR (0.52)	VDR
SCHEMBL14389716	0.85	VDR (0.48)	VDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2419403-B1	VITAMIN D RECEPTOR AGONISTS AND USES THEREOF	VIDASYM INC (US)	2016-09-07	—	—	EP	disclosed