SCHEMBL1805959

SCHEMBL1805959

NC(=O)c1ccc2c(S(=O)(=O)O)cccc2c1[O]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.53
CYP1A2 P05177 2/20 0.44
AURKA O14965 1/20 0.40
AURKB Q96GD4 1/20 0.40
ATIC P31939 2/20 0.39
CDK2 P24941 1/20 0.39
KMT2A Q03164 2/20 0.38
ATM Q13315 2/20 0.38
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 2/20 0.37
GAA P10253 1/20 0.37
APEX1 P27695 1/20 0.36
SUMO2 P61956 2/20 0.35
SUMO1 P63165 2/20 0.35
SENP7 Q9BQF6 2/20 0.35
SENP2 Q9HC62 2/20 0.35
MEN1 O00255 1/20 0.35
NSD2 O96028 1/20 0.35
POLB P06746 1/20 0.35
IDE P14735 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1807803 0.87 CDK2 (0.54) TTRATICCDK2KMT2AATM
SCHEMBL1805677 0.85 TTR (0.50) TTRCYP1A2AURKAAURKBATIC
SCHEMBL10780147 0.84 TTR (0.53) TTRCYP1A2AURKAAURKBATIC
SCHEMBL1805961 0.84 TTR (0.53) TTRCYP1A2AURKAAURKBATIC
SCHEMBL1805693 0.82 CYP2C9 (0.43) TTRCYP1A2KMT2AATMKDM4E
SCHEMBL11143006 0.79 TTR (0.58) TTRCYP1A2AURKAAURKBATIC
SCHEMBL30233642 0.76 TTR (0.75) TTRCYP1A2AURKAAURKBATIC
SCHEMBL29363198 0.76 TTR (0.75) TTRCYP1A2AURKAAURKBATIC
SCHEMBL6242 0.76 TTR (0.75) TTRCYP1A2AURKAAURKBATIC
SCHEMBL1805807 0.75 TTR (0.53) TTRCYP1A2AURKAAURKBATIC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 TTR 594/4885CYP1A2 487/4885AURKA 2276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.