SCHEMBL18065752

SCHEMBL18065752

Cc1onc(-c2ccccc2Cl)c1C(=O)N(C)c1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 20/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2C19 P33261 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29791377 1.00 GPBAR1 (1.00) GPBAR1CYP3A4CYP2C19
SCHEMBL15896190 0.87 GPBAR1 (1.00) GPBAR1CYP3A4CYP2C19
SCHEMBL24212392 0.85 GPBAR1 (1.00) GPBAR1CYP3A4CYP2C19
SCHEMBL3545014 0.85 GPBAR1 (0.79) GPBAR1CYP3A4CYP2C19
SCHEMBL24212391 0.83 GPBAR1 (1.00) GPBAR1CYP3A4CYP2C19
SCHEMBL27910275 0.79 HSD17B10 (0.78) GPBAR1CYP3A4CYP2C19
SCHEMBL14765558 0.78 MAPT (0.77) GPBAR1CYP3A4CYP2C19
SCHEMBL32679558 0.78 HSD17B10 (0.76) GPBAR1CYP3A4CYP2C19
SCHEMBL315858 0.78 HSD17B10 (0.76) GPBAR1CYP3A4CYP2C19
SCHEMBL30395456 0.78 HSD17B10 (0.76) GPBAR1CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1510 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122065240-A CR-RF hybrid model-based large-range fir accumulation estimation method and system 福建师范大学 2026-05-19 CN claimed
CN-122005490-A Drug delivery system of targeted neutrophil extracellular trap net and preparation method and application thereof 河南医药大学 2026-05-12 CN claimed
EP-4689104-A1 WOOLLY MAMMOTH SPECIFIC GENE VARIANTS AND COMPOSITIONS COMPRISING SAME Colossal Biosciences Inc. (US) 2026-02-11 EP claimed
CN-119913250-A Primer composition, kit and method for detecting mutation of benign and malignant thyroid nodule related genes 济南金域医学检验中心有限公司 2025-05-02 CN claimed
CN-119830696-A Forest disturbance prediction method and system based on optics and SAR dense time sequence Informer model 内江师范学院 2025-04-15 CN claimed
CN-116425990-B Chiral dicarboxylic acid metal organic framework crystal material and preparation method and application thereof 遵义医科大学 2025-03-21 CN claimed
CN-119580917-A Early lung cancer screening database management system 陕西省人民医院(陕西省临床医学研究院) 2025-03-07 CN claimed
CN-119530373-A Use of CCDC134 in bone dysplasia disorders 北京大学 2025-02-28 CN claimed
CN-119433017-A Application of CCDC71L in diagnosis and treatment of radiation enteritis 核工业四一六医院 2025-02-14 CN claimed
CN-117965595-B Novel application of ccdC gene 南京林业大学 2025-01-28 CN claimed
CN-110890135-B Prediction method of energetic N-oxide crystal structure 西安近代化学研究所 2022-05-24 CN claimed
CN-114466662-A Use of FGFR inhibitors in cancers with genetically altered FGFR to enhance patient response to immune checkpoint inhibitors in a sequential therapy setting 詹森药业有限公司 2022-05-10 CN claimed
WO-2022075478-A1 THERAPEUTIC AGENT FOR GLIOBLASTOMA, SCREENING METHOD, EFFICACY DETERMINATION METHOD, AND PROGNOSIS DETERMINATION METHOD 国立大学法人東北大学 2022-04-14 WO claimed
CN-114317753-A Detection model of eye tumor fusion gene, construction method and detection method 北京迈基诺基因科技股份有限公司 2022-04-12 CN claimed
CN-111909185-B Blue light excited zinc complex and preparation method and application thereof 河北工业大学 2022-03-01 CN claimed
CN-114120137-A Wetland element space-time evolution monitoring method based on time sequence main remote sensing image 桂林理工大学 2022-03-01 CN claimed
CN-111190007-B Application of CCDC25 in predicting breast cancer prognosis and inhibiting breast cancer distant organ metastasis 中山大学孙逸仙纪念医院 2022-02-25 CN claimed
CN-114057859-A Antiviral target gene of coronavirus including SARS-CoV and SARS-CoV-2 and its application 复旦大学 2022-02-18 CN claimed
WO-2016149299-A1 THERAPEUTIC COMPOUNDS THAT SUPPRESS PROTEIN ARGININE METHYLTRANSFERASE ACTIVITY FOR REDUCING TUMOR CELL PROLIFERATION EPINOVA THERAPEUTICS CORP. (US) 2016-09-22 WO claimed
US-20160271149-A1 THERAPEUTIC COMPOUNDS THAT SUPPRESS PROTEIN ARGININE METHYLTRANSFERASE ACTIVITY FOR REDUCING TUMOR CELL PROLIFERATION EPINOVA THERAPEUTICS CORP. 2016-09-22 US claimed