SCHEMBL32679558

SCHEMBL32679558

Cc1onc(-c2ccccc2Cl)c1C(=O)Cl

nearest known ligand 0.76

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.76
GPBAR1 Q8TDU6 7/20 0.67
LMNA P02545 1/20 0.67
CYP2C19 P33261 2/20 0.64
ALDH1A1 P00352 1/20 0.64
NPC1 O15118 1/20 0.64
MAPT P10636 2/20 0.63
PLAU P00749 1/20 0.63
ELANE P08246 1/20 0.63
EPAS1 Q99814 1/20 0.63
CYP3A4 P08684 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.62
USP2 O75604 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL315858 1.00 HSD17B10 (0.76) HSD17B10GPBAR1LMNACYP2C19ALDH1A1
SCHEMBL27910275 0.89 HSD17B10 (0.78) HSD17B10GPBAR1LMNACYP2C19ALDH1A1
SCHEMBL10520547 0.88 HSD17B10 (0.76) HSD17B10GPBAR1LMNACYP2C19MAPT
SCHEMBL459354 0.88 HSD17B10 (0.76) HSD17B10GPBAR1LMNACYP2C19ALDH1A1
SCHEMBL30395456 0.88 HSD17B10 (0.76) HSD17B10GPBAR1LMNACYP2C19ALDH1A1
Hydrochloric Acid SCHEMBL11554371 0.87 HSD17B10 (0.74) HSD17B10GPBAR1LMNACYP2C19ALDH1A1
SCHEMBL8548060 0.87 HSD17B10 (0.74) HSD17B10GPBAR1LMNACYP2C19ALDH1A1
SCHEMBL903109 0.87 HSD17B10 (1.00) HSD17B10GPBAR1LMNACYP2C19ALDH1A1
SCHEMBL14765558 0.85 MAPT (0.77) HSD17B10GPBAR1LMNACYP2C19ALDH1A1
SCHEMBL3451560 0.84 TSHR (0.75) GPBAR1LMNAALDH1A1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121181573-B Cephalosporium containing C-3 tetrahydrofuran derivative and application thereof 重庆汉佩生物科技有限公司 2026-02-27 CN disclosed