Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.53 |
| ▸ | MGAM | O43451 | 2/20 | 0.53 |
| ▸ | SI | P14410 | 2/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18065782 | 0.88 | RAB9A (0.54) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL9330668 | 0.86 | KDM4E (0.69) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL30714914 | 0.86 | KDM4E (0.69) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL30714876 | 0.79 | KDM4E (0.69) | GAAKDM4ERAB9AMAPTNPC1 | |
| SCHEMBL13866522 | 0.79 | RAB9A (0.58) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL13866510 | 0.77 | RAB9A (0.57) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL24466846 | 0.77 | KDM4E (0.62) | GAAKDM4ERAB9AMAPTNPC1 | |
| SCHEMBL30714885 | 0.75 | KDM4E (0.59) | GAAKDM4ERAB9AMAPTNPC1 | |
| SCHEMBL28448514 | 0.74 | MAPT (0.47) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL16341043 | 0.74 | KDM4E (0.71) | GAAKDM4ERAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9954257-B2 | Fluorescent indicator of lithium ions and related methods | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2018-04-24 | — | — | US | disclosed |
| US-9954257-B2 | Fluorescent indicator of lithium ions and related methods | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2018-04-24 | — | — | US | disclosed |
| US-20160276717-A1 | FLUORESCENT INDICATOR OF LITHIUM IONS AND RELATED METHODS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2016-09-22 | — | — | US | disclosed |
| US-20160276717-A1 | FLUORESCENT INDICATOR OF LITHIUM IONS AND RELATED METHODS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2016-09-22 | — | — | US | disclosed |