Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18070443 | 0.97 | FOLH1 (0.48) | FOLH1PRMT1TMEM97SIGMAR1CHRM2 | |
| SCHEMBL18070666 | 0.91 | FOLH1 (0.51) | FOLH1PRMT1TMEM97SIGMAR1CHRM2 | |
| SCHEMBL12304491 | 0.88 | FOLH1 (0.40) | FOLH1PRMT1LMNAMAPTMEN1 | |
| SCHEMBL25986897 | 0.87 | FOLH1 (0.41) | FOLH1PRMT1TMEM97SIGMAR1CHRM2 | |
| SCHEMBL18070440 | 0.87 | FOLH1 (0.41) | FOLH1PRMT1TMEM97SIGMAR1CHRM2 | |
| SCHEMBL12304490 | 0.85 | MAPT (0.47) | FOLH1PRMT1LMNAMAPTMEN1 | |
| SCHEMBL21314815 | 0.85 | FOLH1 (0.41) | FOLH1PRMT1LMNAMAPTMEN1 | |
| SCHEMBL21314812 | 0.85 | FOLH1 (0.41) | FOLH1PRMT1LMNAMAPTMEN1 | |
| SCHEMBL15996382 | 0.84 | LMNA (0.44) | LMNAMAPTMEN1NPC1USP2 | |
| SCHEMBL12690873 | 0.84 | LMNA (0.44) | LMNAMAPTMEN1NPC1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160263249-A1 | NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160263249-A1 | NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF | CD68, MSR1, CD47 | FOLH1 134/4885PRMT1 3727/4885TMEM97 2327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.