Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18049017 | 0.86 | KDR (0.47) | KDRRXFP1MEN1MAPTKMT2A | |
| SCHEMBL18070874 | 0.86 | KDR (0.47) | KDRRXFP1MEN1MAPTKMT2A | |
| SCHEMBL18070993 | 0.85 | KDR (0.48) | KDRRXFP1MEN1MAPTKMT2A | |
| SCHEMBL18048968 | 0.84 | KDR (0.58) | KDRRXFP1MEN1MAPTKMT2A | |
| SCHEMBL18049023 | 0.81 | KDR (0.46) | KDRRXFP1MEN1MAPTKMT2A | |
| SCHEMBL18070901 | 0.81 | KDR (0.46) | KDRRXFP1MEN1MAPTKMT2A | |
| SCHEMBL18070900 | 0.81 | KDR (0.46) | KDRRXFP1MEN1MAPTKMT2A | |
| SCHEMBL18049838 | 0.79 | KDR (0.52) | KDRRXFP1MEN1MAPTKMT2A | |
| SCHEMBL18049791 | 0.76 | KDR (0.61) | KDRRXFP1MEN1MAPTKMT2A | |
| SCHEMBL18071012 | 0.75 | KDR (0.48) | KDRRXFP1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144797-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | disclosed |