Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 8/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | USP36 | Q9P275 | 4/20 | 0.36 |
| ▸ | KDR | P35968 | 4/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18070942 | 1.00 | SCN10A (0.43) | SCN10AIDO1TDO2WNT1USP36 | |
| SCHEMBL18070898 | 0.86 | MAPT (0.48) | IDO1TDO2KDRMAPT | |
| SCHEMBL18070893 | 0.86 | MAPT (0.48) | IDO1TDO2KDRMAPT | |
| SCHEMBL18048941 | 0.86 | MAPT (0.48) | IDO1TDO2KDRMAPT | |
| SCHEMBL18070941 | 0.86 | KDR (0.52) | SCN10AKDRMAPT | |
| SCHEMBL18048990 | 0.86 | KDR (0.52) | SCN10AKDRMAPT | |
| SCHEMBL18070948 | 0.86 | KDR (0.52) | SCN10AKDRMAPT | |
| SCHEMBL18048937 | 0.84 | MAPT (0.48) | IDO1TDO2KDRMAPT | |
| SCHEMBL18070929 | 0.84 | MAPT (0.48) | IDO1TDO2KDRMAPT | |
| SCHEMBL18070978 | 0.84 | MAPT (0.48) | IDO1TDO2KDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144797-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | disclosed |