Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.53 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.35 |
| ▸ | CCND1 | P24385 | 2/20 | 0.35 |
| ▸ | CCND2 | P30279 | 2/20 | 0.35 |
| ▸ | CCND3 | P30281 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11924989 | 0.85 | CA12 (0.57) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL29941410 | 0.85 | CA12 (0.57) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL27256571 | 0.81 | CA12 (0.53) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL5197627 | 0.81 | CA12 (0.53) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL7371817 | 0.79 | CA12 (0.50) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL28399521 | 0.77 | CA12 (0.52) | CA12CA9BRPF1BRD4KAT2B | |
| Hydrochloric Acid SCHEMBL18168120 | 0.75 | HTR2A (0.47) | BRPF1MAPTLMNAHTR2AHTR2C | |
| SCHEMBL7957507 | 0.73 | CA12 (0.47) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL19892640 | 0.70 | CA12 (0.45) | CA12CA9BRPF1BRD4KAT2B | |
| SCHEMBL15621874 | 0.70 | CA12 (0.44) | CA12CA9BRPF1BRD4KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120294808-A1 | Fluorescent Analogs of Neurotransmitters, Compositions Containing the Same and Methods of Using the Same | UNIVERSITY OF MIAMI (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2011057229-A2 | FLUORESCENT ANALOGS OF NEUROTRANSMITTERS, COMPOSITIONS CONTAINING THE SAME AND METHODS OF USING THE SAME | UNIVERSITY OF MIAMI (US) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120294808-A1 | Fluorescent Analogs of Neurotransmitters, Compositions Containing the Same and Methods of Using the Same | HRH3, CHRNA4, HRH4 | CA12 2087/4885CA9 1570/4885BRPF1 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.