Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.39 |
| ▸ | PRKCG | P05129 | 3/20 | 0.39 |
| ▸ | PRKCB | P05771 | 3/20 | 0.39 |
| ▸ | PRKCA | P17252 | 3/20 | 0.39 |
| ▸ | PRKCH | P24723 | 3/20 | 0.39 |
| ▸ | PRKCI | P41743 | 3/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.38 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10335519 | 0.93 | DNM1 (0.38) | DNM1LMNAPRKD3PRKCGPRKCB | |
| SCHEMBL16317815 | 0.90 | DNM1 (0.48) | DNM1ZDHHC7LMNAPRKD3PRKCG | |
| SCHEMBL17526936 | 0.90 | DNM1 (0.48) | DNM1ZDHHC7LMNAPRKD3PRKCG | |
| SCHEMBL1142232 | 0.90 | DNM1 (0.48) | DNM1ZDHHC7LMNAPRKD3PRKCG | |
| SCHEMBL17526680 | 0.90 | DNM1 (0.48) | DNM1ZDHHC7LMNAPRKD3PRKCG | |
| SCHEMBL14520047 | 0.87 | TSHR (0.44) | DNM1ZDHHC7LMNAPRKD3PRKCG | |
| SCHEMBL18165672 | 0.87 | TSHR (0.44) | DNM1ZDHHC7LMNAPRKD3PRKCG | |
| SCHEMBL13464149 | 0.87 | TSHR (0.44) | DNM1ZDHHC7LMNAPRKD3PRKCG | |
| SCHEMBL17676329 | 0.87 | TSHR (0.44) | DNM1ZDHHC7LMNAPRKD3PRKCG | |
| SCHEMBL17526806 | 0.87 | DNM1 (0.43) | DNM1ZDHHC7LMNAPRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264968-A1 | MODIFIED iRNA AGENTS | ALNYLAM PHARMACEUTICALS, INC. | 2016-09-15 | — | — | US | disclosed |