Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18072326 | 0.82 | EGLN3 (0.53) | EGLN3NAMPTFPR3FPR2LOXL2 | |
| SCHEMBL20445070 | 0.82 | EGLN3 (0.53) | EGLN3NAMPTFPR3FPR2LOXL2 | |
| SCHEMBL19755640 | 0.78 | EGLN3 (0.49) | EGLN3NAMPTFPR3FPR2LOXL2 | |
| SCHEMBL4517015 | 0.75 | EGLN3 (0.44) | EGLN3NAMPTFPR3FPR2LOXL2 | |
| SCHEMBL23609328 | 0.75 | EGLN3 (0.44) | EGLN3NAMPTFPR3FPR2LOXL2 | |
| SCHEMBL20942726 | 0.74 | EGLN3 (0.45) | EGLN3NAMPTFPR3FPR2LOXL2 | |
| SCHEMBL18381426 | 0.74 | EGLN3 (0.61) | EGLN3NAMPTFPR3FPR2LOXL2 | |
| SCHEMBL29531015 | 0.74 | NAMPT (0.54) | EGLN3NAMPTLOXL2HDAC1HDAC6 | |
| SCHEMBL23609337 | 0.74 | EGLN3 (0.45) | EGLN3NAMPTFPR3FPR2CYP1A2 | |
| SCHEMBL3507025 | 0.74 | EGLN3 (0.56) | EGLN3FPR3FPR2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144703-A1 | FLUORINATED LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2016-09-15 | — | — | WO | disclosed |