Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 4/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PPP1CC | P36873 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18073230 | 0.90 | PPM1B (0.63) | PPM1BPTPN1PPP1CCCYP3A4TSHR | |
| SCHEMBL18073231 | 0.89 | PPM1B (0.48) | PPM1BPTPN1PPP1CCCYP3A4TSHR | |
| SCHEMBL18073234 | 0.82 | TFPI2 (0.50) | PPM1BPTPN1PPP1CCTSHRALDH1A1 | |
| SCHEMBL18073210 | 0.77 | PPM1B (0.50) | PPM1BPTPN1PPP1CCSLC6A4SLC6A3 | |
| SCHEMBL27761807 | 0.75 | PPM1B (0.67) | PPM1BPTPN1PPP1CCTSHRNAAA | |
| SCHEMBL27783707 | 0.75 | PPM1B (0.67) | PPM1BPTPN1PPP1CCTSHRNAAA | |
| SCHEMBL27783597 | 0.75 | PPM1B (0.67) | PPM1BPTPN1PPP1CCTSHRNAAA | |
| SCHEMBL27783556 | 0.75 | PPM1B (0.67) | PPM1BPTPN1PPP1CCTSHRNAAA | |
| SCHEMBL27783538 | 0.75 | PPM1B (0.71) | PPM1BPTPN1PPP1CCTSHRKDM4E | |
| SCHEMBL8080046 | 0.72 | PPM1B (0.84) | PPM1BPTPN1PPP1CCSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264593-A1 | PROTEIN PHOSPHATASE INHIBITORS THAT CROSS THE BLOOD BRAIN BARRIER | LIXTE BIOTECHNOLOGY, INC. | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264593-A1 | PROTEIN PHOSPHATASE INHIBITORS THAT CROSS THE BLOOD BRAIN BARRIER | DUSP1, PPP5C, DUSP15 | PPM1B 42/4885PTPN1 85/4885PPP1CC 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.