DUSP15 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL13736685	1.00	2/20
SCHEMBL15829189	1.00	2/20
SCHEMBL18230879	0.81	2/20
SCHEMBL15829194	0.80	2/20
SCHEMBL15829188	0.78	2/20
SCHEMBL15829190	0.78	2/20
SCHEMBL15829193	0.77	2/20
SCHEMBL18230880	0.76	2/20
SCHEMBL15829191	0.75	2/20
SCHEMBL15829185	0.67	2/20
SCHEMBL18230877	0.67	2/20
SCHEMBL18231230	0.66	2/20
SCHEMBL15829192	0.65	2/20
SCHEMBL15829168	0.65	2/20
SCHEMBL15829166	0.62	2/20
SCHEMBL15829167	0.60	2/20
SCHEMBL15829187	0.59	2/20
SCHEMBL15829172	0.58	2/20
SCHEMBL15829183	0.57	2/20
SCHEMBL15829184	0.53	2/20

Clinical trials — most relevant to DUSP15 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Rapid Effects of Hydrocortisone on Glucose-induced Insulin Secretion in Healthy Humans	PHASE4	COMPLETED
Cyclosporine For The Treatment Of COVID-19(+)	PHASE2	COMPLETED
Lapatinib Ditosylate in Treating Patients With Unresectable Liver or Biliary Tract Cancer	PHASE2	COMPLETED
Pembrolizumab (MK-3475) in MM Patients With Residual Disease	PHASE2	COMPLETED
Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple Myeloma	PHASE1/PHASE2	SUSPENDED
Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer	PHASE2	COMPLETED
Sorafenib Tosylate and Bevacizumab in Treating Patients With Advanced Kidney Cancer	PHASE1/PHASE2	COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome	PHASE1	COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
Phase I Study of SC-43 Oral Solution in Subjects With Refractory Solid Tumors	PHASE1	WITHDRAWN
Palliative Thoracic Radiotherapy Plus BKM120	PHASE1	COMPLETED
Bioequivalence Study of Tacrolimus in Healthy Volunteers	PHASE1	COMPLETED
Quantification of GADD34 Expression in RA	nan	COMPLETED
Lymphoid Tyrosine Phosphatase Gene Polymorphisms in Inflammatory Bowel Disease	nan	UNKNOWN
Clinical Research for Azacitidine Combined With Low-dose Dasatinib in Maintenance Therapy of Acute Myeloid Leukemia	nan	UNKNOWN
NGS in Gallbladder Cancer and Response to Treatment	nan	RECRUITING
Biomarkers in Samples From Patients With Chronic Lymphocytic Leukemia Treated on Clinical Trial ECOG-2997	nan	COMPLETED
Studies of the Tumour Suppressor Gene PTEN - Endometrial Cancer	nan	COMPLETED
Pathological and Nuclear Medicine Factors for Prognosis in Lung Carcinoma	nan	COMPLETED
Uncovering Genes Behind Cartilage Tumors and Vascular Anomalies Using Genomic Sequencing	nan	RECRUITING
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)	nan	COMPLETED
Identification of Novel Targetable Kinases in SR-a GvHD	nan	COMPLETED
Study of Proteins in Head and Neck Cancer Cells	nan	COMPLETED
The Effect of 0.1% Topical Ciclosporin A for 12-weeks on the Eye Surface Immune Cells in Dry Eyes	nan	RECRUITING
Ischemic Preconditioning - Perspectives of Use Vivio/in Vitro Studies	nan	ENROLLING_BY_INVITATION
What is the Impact of TKI on Thyroid Function in CML Patients?	nan	NOT_YET_RECRUITING
Role of NFKBIA and PTPN22 Genes Polymorphism in Acute Rejection Susceptibility After Living Donor Liver Transplantation in Egyptian Patients.	nan	COMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
CircularRNA-microRNA-mRNA Regulatory Axis in IVF	nan	NOT_YET_RECRUITING
Partial PTEN Deletion in Breast Cancer	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a DUSP15 binder may also engage these)

Protein	Name	Similarity
P79348	—	0.991	P79348 →
Q8N5Z5	—	0.987	Q8N5Z5 →
P79209	—	0.987	P79209 →
Q15583	—	0.985	Q15583 →
Q9JL16	—	0.985	Q9JL16 →
Q8BLR5	—	0.985	Q8BLR5 →
Q8WTX9	—	0.985	Q8WTX9 →
O76081	—	0.985	O76081 →
PGF	Placenta growth factor	0.984	landscape →
Q3UIZ8	—	0.984	Q3UIZ8 →
Q7TSF4	—	0.984	Q7TSF4 →
USP19	Ubiquitin carboxyl-terminal hydrolase 19	0.983	landscape →
Q9Y6S9	—	0.983	Q9Y6S9 →
Q80UW3	—	0.983	Q80UW3 →
Q2TBC4	—	0.982	Q2TBC4 →
Q80UE6	—	0.982	Q80UE6 →
Q8VDG6	—	0.982	Q8VDG6 →
Q8NDX1	—	0.982	Q8NDX1 →
Q63572	—	0.981	Q63572 →
Q4R6Y5	—	0.981	Q4R6Y5 →
P03232	—	0.981	P03232 →
Q8WWF5	—	0.981	Q8WWF5 →
Q9BXU2	—	0.981	Q9BXU2 →
TESK1	Dual specificity testis-specific protein kinase 1	0.981	landscape →
Q8BV79	—	0.981	Q8BV79 →
P0C6A0	—	0.981	P0C6A0 →
A0A0D9SF12	—	0.980	A0A0D9SF12 →
A6NMD0	—	0.980	A6NMD0 →
Q8BWG4	—	0.980	Q8BWG4 →
Q9Y2Y4	—	0.980	Q9Y2Y4 →