SCHEMBL1807324

SCHEMBL1807324

C=CC(=O)OC(CCCC)(CCCC)CP(=O)(O)O

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
HPGD P15428 1/20 0.42
FDPS P14324 11/20 0.36
THRB P10828 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
SMPD1 P17405 3/20 0.33
GGPS1 O95749 7/20 0.33
LPAR2 Q9HBW0 1/20 0.32
LPAR3 Q9UBY5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1804830 0.83 THRB (0.37) TSHRHPGDTHRB
SCHEMBL128680 0.82 TSHR (0.40) TSHRHPGDFDPSTHRBSMPD1
SCHEMBL3247446 0.82 TSHR (0.48) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL11032304 0.80 TSHR (0.47) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL8925191 0.79 TSHR (0.46) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL1805860 0.78 TSHR (0.40) TSHRFDPSSMPD1GGPS1LPAR2
SCHEMBL27651693 0.78 TSHR (0.44) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL3247328 0.77 TSHR (0.47) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL5425925 0.77 LPAR3 (0.42) TSHRHPGDFDPSSMPD1GGPS1
SCHEMBL3234096 0.76 TSHR (0.50) TSHRHPGDTHRBZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120299221-A1 MAGNETIC REVERSIBLY ATTACHED TEMPLATE (MRAT) AND USES THEREFOR VANDERBILT UNIVERSITY (US) 2012-11-29 US disclosed
WO-2011068951-A1 MAGNETIC REVERSIBLY ATTACHED TEMPLATE (MRAT) AND USES THEREFOR VANDERBILT UNIVERSITY (US) 2011-06-09 WO disclosed
US-20110111978-A1 DIVERSE CHEMICAL LIBRARIES BOUND TO SMALL PARTICLES WITH PARAMAGNETIC PROPERTIES BIO-RAD LABORATORIES, INC. (US) 2011-05-12 US disclosed
WO-2010011775-A2 DETECTION AND QUANTIFICATION OF ANTIGENS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2010-01-28 WO disclosed
US-20090247421-A1 DIVERSE CHEMICAL LIBRARIES BOUND TO SMALL PARTICLES WITH PARAMAGNETIC PROPERTIES BOSCHETTI EGISTO 2009-10-01 US disclosed
US-20080108123-A1 MAGNETIC SUBSTANCE-BIOSUBSTANCE COMPLEX STRUCTURE, PEPTIDE FRAGMENT CAPABLE OF LINKING TO MAGNETIC SUBSTANCE AND GENE THEREFOR, AND PROCESS FOR PRODUCING THE COMPLEX STRUCTURE CANON KABUSHIKI KAISHA (JP) 2008-05-08 US disclosed
US-7354995-B2 Magnetic substance-biosubstance complex structure, peptide fragment capable of linking to magnetic substance and gene therefor, and process for producing the complex structure CANON KABUSHIKI KAISHA (JP) 2008-04-08 US disclosed
EP-1871726-A2 DIVERSE CHEMICAL LIBRARIES BOUND TO SMALL PARTICLES WITH PARAMAGNETIC PROPERTIES Bio-Rad Laboratories, Inc. (US) 2008-01-02 EP disclosed
US-20070054315-A1 Magnetic substance-biosubstance complex structure, peptide fragment capable of linking to magnetic substance and gene therefor, and process for producing the complex structure CANON KABUSHIKI KAISHA (JP) 2007-03-08 US disclosed
WO-2006102542-A2 DIVERSE CHEMICAL LIBRARIES BOUND TO SMALL PARTICLES WITH PARAMAGNETIC PROPERTIES BIO-RAD LABORATORIES, INC. (US) 2006-09-28 WO disclosed
WO-2004097416-A1 MAGNETIC SUBSTANCE-BIOSUBSTANCE COMPLEX STRUCTURE, PEPTIDE FRAGMENT CAPABLE OF LINKING TO MAGNETIC SUBSTANCE AND GENE THEREFOR, AND PROCESS FOR STRUCTURE CANON KABUSHIKI KAISHA (JP) 2004-11-11 WO disclosed
EP-0743564-B1 Toner for developing electrostatic image and process for production thereof CANON KK (JP) 2001-01-17 EP disclosed
US-5863697-A ADDITION POLYMERIZING TO FORM TONER PARTICLES WHICH HAS A CORE COMPOSED OF A LOW-TEMPERATURE SOFTENING RESIN, AN INNER LAYER ENCLOSING THE CORE AND AN OUTER LAYER, STAINING WITH TRIRUTHENIUM TETROXIDE AND TRIOSMIUM TETROXIDE CANON KABUSHIKI KAISHA (JP) 1999-01-26 US disclosed
US-5795694-A LOW TEMPERATURE SOFTENING CORE CANON KABUSHIKI KAISHA (JP) 1998-08-18 US disclosed
EP-0743564-A2 Toner for developing electrostatic image and process for production thereof CANON KABUSHIKI KAISHA (JP) 1996-11-20 EP disclosed