SCHEMBL1807429

SCHEMBL1807429

O=S(=O)(O)c1ccc(O)c(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
HSD17B10 Q99714 4/20 0.59
KDM4E B2RXH2 1/20 0.53
HPGD P15428 1/20 0.53
PTGS1 P23219 1/20 0.51
PTGS2 P35354 1/20 0.51
TSHR P16473 3/20 0.48
LMNA P02545 1/20 0.48
HSD17B3 P37058 1/20 0.47
HSD17B2 P37059 1/20 0.47
SERPINE1 P05121 3/20 0.45
CA2 P00918 3/20 0.45
CA1 P00915 2/20 0.45
CA12 O43570 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL306418 1.00 ALDH1A1 (0.59) ALDH1A1HSD17B10KDM4EHPGDPTGS1
SCHEMBL306416 0.98 ALDH1A1 (0.57) ALDH1A1HSD17B10KDM4EHPGDPTGS1
SCHEMBL10422850 0.84 ALDH1A1 (0.55) ALDH1A1HSD17B10KDM4EHPGDPTGS1
SCHEMBL9341624 0.84 GAA (0.57) ALDH1A1HSD17B10PTGS1PTGS2TSHR
SCHEMBL29598983 0.84 GAA (0.57) ALDH1A1HSD17B10PTGS1PTGS2TSHR
SCHEMBL68932 0.84 GAA (0.57) ALDH1A1HSD17B10PTGS1PTGS2TSHR
SCHEMBL1803937 0.83 PTGS1 (0.66) KDM4EPTGS1PTGS2CA2CA1
SCHEMBL2649250 0.83 PTGS1 (0.51) ALDH1A1HSD17B10PTGS1PTGS2TSHR
SCHEMBL29389290 0.82 APEX1 (0.48) ALDH1A1HSD17B10KDM4EHPGDTSHR
SCHEMBL474108 0.82 APEX1 (0.48) ALDH1A1HSD17B10KDM4EHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108610247-A The preparation method of the chloro- 7- hydroxide radical-1-indenones of 6- 湖南华腾制药有限公司 2018-10-02 CN claimed
EP-0172298-B1 METHOD FOR MAKING THIOETHER(BISPHTHALIMIDE)S GENERAL ELECTRIC COMPANY (US) 1991-09-11 EP claimed
EP-0227931-B1 A METHOD FOR PRODUCING CYCLOALKANOLS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-09-11 EP claimed
US-4691064-A CATALYST OF AROMATIC SULFONIC ACID HAVING AT LEAST ONE HYDROXYL OR ETHER GROUP SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-01 US claimed
EP-0227931-A2 A method for producing cycloalkanols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-07-08 EP claimed
US-4171459-A Manufacture of α-naphthol BASF AKTIENGESELLSCHAFT (DE) 1979-10-16 US claimed
US-20230333474-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION COMPRISING FLUOROALKYL GROUP-CONTAINING ORGANIC ACID OR SALT THEREOF NISSAN CHEMICAL CORPORATION (JP) 2023-10-19 US disclosed
CN-105027005-B Composition for forming resist underlayer film containing aryl sulfonate having hydroxyl group 日产化学工业株式会社 2020-02-07 CN disclosed
CN-108610247-A The preparation method of the chloro- 7- hydroxide radical-1-indenones of 6- 湖南华腾制药有限公司 2018-10-02 CN disclosed
US-9395628-B2 Resist underlayer film-forming composition containing aryl sulfonate salt having hydroxyl group NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-07-19 US disclosed
US-20150378260-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING ARYL SULFONATE SALT HAVING HYDROXYL GROUP NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-31 US disclosed
US-8470860-B2 Phenyl-sulfamates as aromatase inhibitors STERIX LIMITED (GB) 2013-06-25 US disclosed
US-8470860-B2 Phenyl-sulfamates as aromatase inhibitors STERIX LIMITED (GB) 2013-06-25 US disclosed
EP-0167858-A1 Fiber-reactive disazo compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-01-15 EP disclosed
US-4540832-A Process for the preparation of 6-chloro-2,4-dinitrophenol HOECHST AKTIENGESELLSCHAFT (DE) 1985-09-10 US disclosed
US-4343767-A FOR TRACE ANALYSIS OF PHENOLIC AND HALOGENATED PHENOLIC SPECIES THE DOW CHEMICAL COMPANY (US) 1982-08-10 US disclosed
US-4171459-A Manufacture of α-naphthol BASF AKTIENGESELLSCHAFT (DE) 1979-10-16 US disclosed
US-4143050-A MANUFACTURE OF 3-HALOSULFONYLTHIOPHENE-CARBOXYLIC ACID COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1979-03-06 US disclosed
US-4126696-A 4-ALKYLSULFONYLOXYPHENYL N-ALKYLTHIOLCARBAMATES AND USE THEREOF AS FUNGICIDE FOR AGRICULTURE NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1978-11-21 US disclosed
US-4117019-A MANUFACTURE OF O-BENZYLTOLUENES BASF AKTIENGESELLSCHAFT (DE) 1978-09-26 US disclosed