Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 6/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18076215 | 0.94 | MALT1 (0.37) | KMT2AALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL15425551 | 0.91 | KMT2A (0.40) | KMT2AALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL15412416 | 0.89 | MALT1 (0.35) | MALT1ELANECTSKADORA2ARXFP1 | |
| Formic Acid SCHEMBL15412152 | 0.89 | KMT2A (0.38) | KMT2AALDH1A1NPSR1KDM4EHPGD | |
| Formic Acid SCHEMBL15412150 | 0.89 | KMT2A (0.37) | KMT2AALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL18043803 | 0.88 | KMT2A (0.45) | KMT2AALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL15412357 | 0.88 | ELANE (0.44) | MALT1ELANECTSKADORA2ATRPV4 | |
| SCHEMBL15412140 | 0.86 | MALT1 (0.36) | MALT1ELANECTSKADORA2AMGAT2 | |
| SCHEMBL15425558 | 0.85 | MALT1 (0.37) | KMT2AALDH1A1NPSR1KDM4EHPGD | |
| Bromide SCHEMBL15412068 | 0.85 | MALT1 (0.36) | KMT2AALDH1A1NPSR1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872509-B1 | INHIBITION OF ENZYMES | CHIESI FARMA SPA (IT) | 2016-09-14 | — | — | EP | disclosed |