Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 6/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL15412068 | 0.99 | MALT1 (0.36) | MALT1ELANEADORA2AALDH1A1NPSR1 | |
| SCHEMBL15425551 | 0.94 | KMT2A (0.40) | MALT1ELANEADORA2AALDH1A1NPSR1 | |
| Formic Acid SCHEMBL15412152 | 0.92 | KMT2A (0.38) | MALT1ELANEADORA2AALDH1A1NPSR1 | |
| SCHEMBL18076215 | 0.92 | MALT1 (0.37) | MALT1ELANEADORA2AALDH1A1NPSR1 | |
| Formic Acid SCHEMBL15412150 | 0.91 | KMT2A (0.37) | MALT1ELANEADORA2AALDH1A1NPSR1 | |
| SCHEMBL15411499 | 0.89 | MALT1 (0.38) | MALT1ELANEADORA2AALDH1A1NPSR1 | |
| SCHEMBL15425572 | 0.88 | ELANE (0.36) | MALT1ELANEADORA2AVNN1RXFP1 | |
| Bromide SCHEMBL15411927 | 0.88 | ELANE (0.36) | MALT1ELANEADORA2AVNN1RXFP1 | |
| SCHEMBL15425389 | 0.88 | ELANE (0.44) | MALT1ELANEADORA2AKDM4EKMT2A | |
| Bromide SCHEMBL15411633 | 0.87 | ELANE (0.44) | MALT1ELANEADORA2AKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199984-B2 | Inhibition of enzymes | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-12-01 | — | — | US | disclosed |
| US-20140018345-A1 | INHIBITION OF ENZYMES | CHIESI FARMACEUTICI S.P.A (IT) | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018345-A1 | INHIBITION OF ENZYMES | SERPINB1, ELANE, MPO | MALT1 4442/4885ELANE 2/4885ADORA2A 1511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.