Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803233 | 0.89 | TSHR (0.54) | TSHRTP53LTB4R2GRM1ALDH1A1 | |
| SCHEMBL1802642 | 0.87 | SLC6A3 (0.41) | TSHRTP53GRM1HDAC1HDAC6 | |
| SCHEMBL29028585 | 0.86 | TSHR (0.39) | TSHRLTB4R2ADRA2CALDH1A1HPGD | |
| SCHEMBL29028410 | 0.86 | KMT2A (0.43) | TSHRTP53LTB4R2ALDH1A1MAPT | |
| SCHEMBL16508384 | 0.85 | TP53 (0.44) | TSHRTP53LTB4R2HDAC1HDAC6 | |
| SCHEMBL29114035 | 0.84 | MEN1 (0.44) | TSHRTP53LTB4R2HDAC1HDAC6 | |
| SCHEMBL30221966 | 0.81 | LTB4R2 (0.40) | TSHRLTB4R2ADRA2CALDH1A1MAPT | |
| SCHEMBL30267012 | 0.81 | LTB4R2 (0.40) | TSHRLTB4R2ADRA2CALDH1A1MAPT | |
| SCHEMBL29028446 | 0.81 | NR1I2 (0.40) | TSHRLTB4R2GRM1ALDH1A1MAPT | |
| SCHEMBL24914648 | 0.80 | LTB4R2 (0.39) | TSHRLTB4R2ADRA2CALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322502-B1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | MITSUI CHEMICALS AGRO INC (JP) | 2019-09-18 | — | — | EP | disclosed |
| EP-2322502-B1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | MITSUI CHEMICALS AGRO INC (JP) | 2019-09-18 | — | — | EP | disclosed |
| US-9890110-B2 | Method for producing amide derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2018-02-13 | — | — | US | disclosed |
| US-9890110-B2 | Method for producing amide derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2018-02-13 | — | — | US | disclosed |
| US-9890110-B2 | Method for producing amide derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2018-02-13 | — | — | US | disclosed |
| US-20160297750-A1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2016-10-13 | — | — | US | disclosed |
| US-20160297750-A1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2016-10-13 | — | — | US | disclosed |
| US-20160297750-A1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2016-10-13 | — | — | US | disclosed |
| US-9394240-B2 | Method for producing amide derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2016-07-19 | — | — | US | disclosed |
| US-9394240-B2 | Method for producing amide derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2016-07-19 | — | — | US | disclosed |
| US-8853440-B2 | Method for producing amide derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2014-10-07 | — | — | US | disclosed |
| US-8853440-B2 | Method for producing amide derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20140296560-A1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140296560-A1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140296560-A1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20110137068-A1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2011-06-09 | — | — | US | disclosed |
| US-20110137068-A1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2011-06-09 | — | — | US | disclosed |
| US-20110137068-A1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2011-06-09 | — | — | US | disclosed |
| EP-2322502-A1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | Mitsui Chemicals Agro, Inc. (JP) | 2011-05-18 | — | — | EP | disclosed |
| EP-2322502-A1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | Mitsui Chemicals Agro, Inc. (JP) | 2011-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296560-A1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | AFF4, AFF1, AFF2 | TSHR 56/4885TP53 4648/4885LTB4R2 1076/4885 |
| US-20160297750-A1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | AFF4, AFF1, AFF2 | TSHR 56/4885TP53 4648/4885LTB4R2 1076/4885 |
| US-20110137068-A1 | METHOD FOR PRODUCING AMIDE DERIVATIVE | AFF4, AFF1, AFF2 | TSHR 56/4885TP53 4648/4885LTB4R2 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.